Resources

Publication

Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway

Author: Y. Guo, M. Shen, Q. Dong, N. M. Méndez-Albelo, S. X. Huang, C. L. Sirois, J. Le, M. Li, E. D. Jarzembowski, K. A. Schoeller, M. E. Stockton, V. L. Horner, A. M. M. Sousa, Y. Gao, Birth Defects Research Laboratory, J. E. Levine, D. Wang, Q. Chang & X. Zhao

Product: Maestro Edge, Neural Module, CytoView MEA Plate,

Evaluation of neurotoxicity for pesticide-related compounds in human iPS cell-derived neurons using microelectrode array

Verification of the seizure liability of compounds based on their in vitro functional activity in cultured rat cortical neurons and co-cultured human iPSC-derived neurons with astrocytes and in vivo extrapolation to cerebrospinal fluid concentration

Modulation of GABAA activity: Investigations in hiPSC-derived neural co-cultures and human ion channel assays

An integrated in vitro approach for early seizure prediction utilising human derived induced pluripotent stem cells and human ion channel assays

An integrated approach for early in vitro seizure prediction utilizing hiPSC neurons and human ion channel assays

Human forebrain organoid-based multi-omics analyses of PCCB as a schizophrenia associated gene linked to GABAergic pathways

Characterization of functional neuronal activity in vitro with local field potential signals

Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity

Comparative study for the IMI2-NeuroDeRisk project on microelectrode arrays to derisk drug-induced seizure liability

NETRI, in collaboration with Axion BioSystems, launches NeuroFluidics™ MEA line, high-throughput MEA-capable organs-on-chip

A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells

Flubendazole exposure disrupts neural development and function of zebrafish embryos (Danio rerio)

Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway

Organoid models of breathing disorders reveal patterning defect of hindbrain neurons caused by PHOX2B-PARMs

Pathophysiological mechanisms in a new form of Charcot Marie Tooth due to a mutation in PDXK

Neuropharmacology of human TERA2.cl.SP12 stem cell-derived neurons in ultra-long-term culture for antiseizure drug discovery

Alzheimer’s Disease

Neurotoxicity of non-volatile and semi-volatile diesel exhaust-derived ultrafine particles

Differential response of C9orf72 transcripts following neuronal depolarization

Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity

Resources

Evaluation of neurotoxicity for pesticide-related compounds in human iPS cell-derived neurons using microelectrode array

Verification of the seizure liability of compounds based on their in vitro functional activity in cultured rat cortical neurons and co-cultured human iPSC-derived neurons with astrocytes and in vivo extrapolation to cerebrospinal fluid concentration

Modulation of GABAA activity: Investigations in hiPSC-derived neural co-cultures and human ion channel assays

An integrated in vitro approach for early seizure prediction utilising human derived induced pluripotent stem cells and human ion channel assays

An integrated approach for early in vitro seizure prediction utilizing hiPSC neurons and human ion channel assays

Human forebrain organoid-based multi-omics analyses of PCCB as a schizophrenia associated gene linked to GABAergic pathways

Characterization of functional neuronal activity in vitro with local field potential signals

Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity

Comparative study for the IMI2-NeuroDeRisk project on microelectrode arrays to derisk drug-induced seizure liability

NETRI, in collaboration with Axion BioSystems, launches NeuroFluidics™ MEA line, high-throughput MEA-capable organs-on-chip

A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells

Flubendazole exposure disrupts neural development and function of zebrafish embryos (Danio rerio)

Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway

Organoid models of breathing disorders reveal patterning defect of hindbrain neurons caused by PHOX2B-PARMs

Pathophysiological mechanisms in a new form of Charcot Marie Tooth due to a mutation in PDXK

Neuropharmacology of human TERA2.cl.SP12 stem cell-derived neurons in ultra-long-term culture for antiseizure drug discovery

Alzheimer’s Disease

Neurotoxicity of non-volatile and semi-volatile diesel exhaust-derived ultrafine particles

Differential response of C9orf72 transcripts following neuronal depolarization

Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity

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