Publication

2021 Nature Molecular Psychiatry bipolar disorder publication
Publication
Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients
Author: Santos R, Linker SB, Stern S, Mendes APD, Shokhirev MN, Erikson G, Randolph-Moore L, Racha V, Kim Y, Kelsoe JR, Bang AG, Alda M, Marchetto MC, Gage FH.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 EMBO Muotri Neural organoids and MEA paper
Publication
Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids
Author: Trujillo CA, Adams JW, Negraes PD, Carromeu C, Tejwani L, Acab A, Tsuda B, Thomas CA, Sodhi N, Fichter KM, Romero S, Zanella F, Sejnowski TJ, Ulrich H, Muotri AR.
Product: Maestro Pro, CytoView MEA Plate, Neural Module,
2020 Publication JACC LEAP and proarrhythmic risks in hiPSC-CMs
Publication
Rapid Assessment of Proarrhythmic Potential Using Human iPSC-Derived Cardiomyocytes
Author: Geiger RM, Klein MG, Fatima N, Goldstein RE, Krantz MJ, Haigney MC, Flagg TP.
Product: Maestro Pro, Cardiac Module, BioCircuit MEA Plate,
2020 Neuron Wang Publication on therapeutics for Alzheimers Disease
Publication
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease
Author: Wang M, Li A, Sekiya M, Beckmann ND, Quan X, Schrode N, Fernando MB, Yu A, Zhu L, Cao J, Lyu L, Horgusluoglu E, Wang Q, Guo L, Wang, Y-S, Neff R, Song W-M, Wang E, Shen Q, Zhou X, Ming C, Ho S-M, Vatansever S, Kaniskan HU, Jin J, Zhou M-M, Ando K, Ho L, Slesinger PA, Yue Z, Zhu J, Katsel P, Gandy S, Ehrlich ME, Fossati V, Noggle S, Cai D, Haroutunian V, Iijima KM, Schadt E, Brennand KJ, Zhang B.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Plos Biology Bauer
Publication
Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C
Author: Bauer L, Manganaro R, Zonsics B, Hurdiss DL, Zwaagstra M, Donselaar T, Welter NGE, van Kleef RGDM, Lopez ML, Bevilacqua F, Raman T, Ferla S, Bassetto M, Neyts J, Strating JRPM, Westerink RHS, Brancale A, van Kuppeveld FJM.
Product: Maestro Pro, Neural Module, BioCircuit MEA Plate,
2020 mechanisms of QT prolongation on MEA system
Publication
Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block
Author: Tran PN, Sheng J, Randolph AL, Baron CA, Thiebaud N, Ren M, Wu M, Johannesen L, Volpe DA, Patel D, Blinova K, Strauss DG and Wu WW.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
2020 publication neuronal medium optimized for optogenetics
Publication
BrainPhys neuronal medium optimized for imaging and optogenetics in vitro
Author: Zabolocki M, McCormack K, van den Hurk M, Milky B, Shoubridge AP, Adams R, Jenne Tran J, Mahadevan-Jansen A, Reineck P, Thomas J, Hutchinson MR, Mak CKH, Añonuevo A, Chew LH, Hirst AJ, Lee VM, Knock E and Bardy C.
Product: Maestro Pro, Neural Module, Lumos MEA Plate, Lumos,
2020 publication on epilepsy and multielectrode array system
Publication
An epilepsy‐associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model
Author: Ahn LY, Coatti GC, Liu J, Gumus E, Schaffer AE, Miranda HC.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Publication on methadone and cortical organoids on MEA system
Publication
Methadone interrupts neural growth and function in human cortical organoids
Author: Yao H, Wu W, Cerf I, Zhao HW, Wang J, Negraes PD, Muotria AR, Haddad GG.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 publication on reduced gaba on neuronal excitability
Publication
Reduced GABAergic Neuron Excitability, Altered Synaptic Connectivity, and Seizures in a KCNT1 Gain-of-Function Mouse Model of Childhood Epilepsy
Author: Shore AN, Colombo S, Tobin WF, Petri S, Cullen ER, Dominguez S, Bostick CD, Beaumont MA, Williams D, Khodagholy D, Yang M, Lutz CM, Peng Y, Gelinas JN, Goldstein DB, Boland MJ, Frankel WN, Weston MC.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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