Maestro Edge

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    Maestro Edge multiwell MEA system
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    Maestro Edge Top Down View
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    Maestro Edge platform with system, software and plates
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Maestro Edge multiwell microelectrode array (MEA) and Impedance system is our most budget-friendly offering, designed for labs with lower throughput needs.  Record from our 6- and 24-well MEA plates, and 96-well impedance plates.

Maestro Edge allows for non-invasive evaluation of your cells in an easy-to-use in vitro assay. Whether monitoring the intricate, electrical activity of excitable cells (e.g. neurons and cardiomyocytes), or tracking the growth and death of cancer cells, Maestro Edge allows you to investigate the functionality of your cells in a multiwell plate.

Key Features

 

 

  • Measure cellular activity label-free and real-time - The Maestro Edge detects key parameters of neural network activity, cardiac functionality, and cell growth, death and attachment.

  • Precisely control the cells environment - Cells are a product of their environment. Maestro Edge has a smart environmental chamber that finely controls temperature and CO₂ while rejecting electrical noise and mechanical vibrations.

  • Connect to your network - 384 simultaneous live recordings from your cells with the Neural and Cardiac modules. Now you can understand life’s circuitry label free in real time in 6- or 24-well plates.

  • Continuous cell monitoring - 96 simultaneous live recordings from your cells with the Impedance module. Track cell proliferation, morphology, and viability in real time.

  • See your cells - Sometimes you just want to look at your cells under a microscope. Maestro’s CytoView patented transparent circuit technology allows cell visualization and assay multiplexing.

  • Control cellular activity - Recreate specific patterns of cellular activity using electrical stimulation or light pluses (with the Lumos optical stimulation system).

  • Start your assay with the push of a button - “One button setup,” means temperature and CO₂ levels automatically adjust on plate docking. Plate usage is logged via an integrated plate barcode scanner for convenient experiment tracking.

  • Monitor the kinetics of your biology on your smartphone - No need to be in lab. With the Impedance module, track changes in cell proliferation, viability, and cell killing over minutes or weeks.

 

Overview

The Maestro Edge multiwell MEA and Impedance system allows you to capture the complex biology of your cells. Whether monitoring the kinetics of cellular growth and death or recording the activity of excitable cells; the Maestro Edge can help you record it noninvasively, in real time, and with software tools to make analysis quick and painless.

Customize your Maestro Edge system for your assay needs:

Maestro Edge platform and compatibility with peripherals, plates, and assay types

 

 

MEA and impedance software

Software

The Maestro Pro platform is available with three software modules: Neural, Cardiac, and Impedance. Select the software modules to match your assay needs:

Neural – Measure the key parameters of neural network function, including activity (are the neurons functional?), synchrony (are the synapses functional?), and oscillation (is the network functional?).

Cardiac – Record the four key measures of functional cardiac performance, label free and in real time in every well of the multiwell plate: action potential (a.k.a. LEAP assay); field potential; propagation; and contractility.

Impedance – Track cell proliferation, morphology, and viability label-free and in real-time. Ideal for immuno-oncology, cytotoxicity, virology, cell migration, cell proliferation, GPCR assays, and many more.

GxP Impedance – Achieve FDA 21 CFR Part 11 compliance in GMP/GLP labs with this version of the Impedance Software Module.

multiwell MEA plates

Consumables

The Maestro Edge system is compatible with the 24- and 6-well versions of Axion’s MEA plates, and the 96-well impedance assay plate. Select the multiwell plates to match your assay needs:

CytoView MEA – The premium Maestro multiwell MEA plate with a transparent well bottom for cell visualization and assay multiplexing. The 24-, and 6-well plate formats are compatible with the Maestro Edge.

BioCircuit MEA – Maestro MEA plates with an opaque well bottom delivering high-quality results at the lowest cost per well. The 24-well plate format is compatible with the Maestro Edge.

Lumos MEA – Maestro MEA plates designed for use with the Lumos system, featuring a transparent well bottom and light-focusing lid. The 24-well plate format is compatible with the Maestro Edge.

CytoView-Z – The Maestro impedance plate with a transparent well bottom for cell visualization and assay multiplexing. Available in a 96-well plate format.

Lumos 96 head for optogenetics

Peripherals

Lumos is a multiwell light stimulation system for optogenetic assays, that pairs with the Maestro Edge. The Maestro Edge platform is compatible with the Lumos 24 optical stimulation system:

Lumos 24 – For use with Lumos MEA 24 plates. The Lumos 24 system has four LEDs per well (red, orange, green and blue).

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