Convergent pathways in idiopathic autism revealed by time course transcriptomic analysis of patient-derived neurons

DeRosa BA, El Hokayem J, Artimovich E, Garcia-Serje C, Phillips AW, Van Booven D, Nestor JE, Wang L, Cuccaro ML, Vance JM, Pericak-Vance MA, Cukier HN, Nestor MW, Dykxhoorn DM.

Sci Rep, 2018

Summary:

Uncover how Maestro technology helped to reveal important insights into common processes altered in early neuronal development that may contribute to ASD pathogenesis. 

Keywords: autism spectrum disorder, ASD, iPSC, neurodevelopmental disorder, differentiation, axon guidance, transcriptome analysis