Dynamical electrical complexity is reduced during neuronal differentiation in autism spectrum disorder

Amatya DN, Linker SB, Mendes APD, Santos R, Erikson G, Shokhirev MN, Zhou Y, Sharpee T, Gage FH, Marchetto MC, Kim Y.

Stem Cell Reports, 2019


Discover how Maestro technology aided researchers in characterizing the dynamic complexity of electrical recordings of stem cell-derived neurons from both individuals with autism spectrum disorder and controls.

Keywords: autism spectrum disorder, ASD, minimum embedding dimension, nonlinear dynamic system, neural activity, neurodevelopment, cell morphology, neuropsychiatric disorder, spatiotemporal analysis