Resources
Toxicological Sciences, 30 July 2026
Publication
Building structure activity relationships to avoid toxicity due to unwanted central nervous system ion channel activity
Author: L. A. K .Zolkiewski, K. L. Rockley, R. A. Roberts, H. G. Jennings, M. Maizières, K. Jones, J. L. McDonagh, K. Newman, E. J. Griffen, J. E. Stacey, and M. J. Morton
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
FENS2026_NeuralNetworkFormationAssay
Poster
Development of a Neural Network Formation Assay for Primary and iPSC-Derived Neural Models
Author: Sullivan, D.D., Ellingson, P., Pires, J., Lindqvist, P., Barnes, S., Streeter, B.W., Passaro, A., Millard, D.C.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Culture Protocol - Cardiac Organoids CytoView MEA
Culture Protocol
Cardiac Organoids on CytoView MEA Protocol
Author: Axion BioSystems
Product: Maestro MEA, Cardiac Module, CytoView MEA Plate,
Nature Communications, 22 July 2026
Publication
Structural insights enable drug discovery for the neuronal NBCn2 carbonate transporter
Author: S. Yang, Y. Zhao, S. Vatansever, G. Zilberg, M. J. Capper, J. Zhang, J. Stamos, K. Hutchinson, A. L. Warren, A. C. Stone, A. Abbassi, E. Purisic, L. Ho, A. Li, J. Dai, A. Schlessinger, B. Zhang, and D. Wacker
Product: Maestro MEA, Neural Module, CytoView MEA Plate,
Science Translational Medicine, 22 July 2026
Publication
Modulating the VIP-VIPR pathway reprograms CAR T cells for superior antitumor efficacy in preclinical cancer models
Author: H. K. Lin, D. A. Blake, R. Freeman, Y. Chen, J. Kim, A. M. Johnson, K. Wells, A. Mudigonda, W. Liu, P. Yadav, F. Zeng, A. Muhuri, K. Min, S. Sarkar, Y. Wang, S. Goyal, R. C. Roberts, E. Christensen, A. B. Ward, B. Heller, P. Chun, J. Dougan, C. C. Porter, B. G. Barwick, C. M. Paulos, L. Yang, A. Patgiri, S. N. Thomas, E. K. Waller, and S. Rafiq
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
“Scalable Hypothalamic Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic Disorders” research publication about generating hypothalamic neurons from human pluripotent stem cells for metabolic disease modeling.
Publication
Scalable hypothalamic neuron differentiation from human pluripotent stem cells suitable for modeling metabolic disorders
Author: V. M. Jovanovic, N. Narisu, L. L. Bonnycastle, D. Castellano, S. Ryu, R. Tharakan, K. T. Mesch, Q. Chen, F. M. B. Erol, H. J. Glover, T. Yan, N. Sinha, C. Sen, S. Yang, D. Blivis, D. F. Bennett, G. Rosales-Soto, J. Inman, P. Ormanoglu, C. A. LeClair, N. D. Shaw, M. Xia, M. Schneider, E. O. Hernandez-Ochoa, M. R. Erdos, A. Simeonov, S. Chen, F. S. Collins, C. A. Doege, and C. A. Tristan
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
NeuroToxicology, 13 July 2026
Publication
Detection of seizurogenic compounds in human and rat neurons in vitro: A multi-laboratory, multi-model assessment
Author: R. Roberts, K. Blinova, C. Carlson, M. Cato, K. Czysz, T. K. Feaster, X. Han, Y. Ishibashi, Y. Kanda, M. Kreir, P. Levesque, N. Miyamoto, J. B. Pierson, T. J. Shafer, S. Schachtele, C. J. Strock, T. Yoshinaga, and I. Suzuki
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Development and Functional Assessment of iPSC-derived Endothelial Cells using a Novel Non-Invasive Workflow
Poster
Development and Functional Assessment of iPSC-derived Endothelial Cells using a Novel Non-Invasive Workflow
Author: Barnes, S., Sullivan, D.D., Ellingson, P., Streeter, B.W., Passaro, A., Millard, D.C.
Product: Omni, Scratch Assay Module, Maestro Z, Impedance Module, CytoView-Z Plate, iPSC Module, Fluorescence Module,
Establishing a functional standard for hiPSC-neural models used to screen for seizure liability with the multielectrode array (MEA) assay
Poster
Establishing a functional standard for hiPSC-neural models used to screen for seizure liability with the multielectrode array (MEA) assay
Author: Mike Clements, Matthew Cato, Khuram W Chaudhary, Stacie Chvatal, Annie Delaunois, Parker Ellingson, Steve Fiene, Catherine Garrison, Mohamed Kreir, Norimasa Miyamoto, Katie Newman, Bumpei Noda, Kimberly L Rockley, Leandro Royer, Timothy J
Shafer, Christopher Strock, Ikuro Suzuki, Anke M Tukker, Remco HS Westerink, Takashi Yoshinaga, and Louisa AK Zolkiewski
Product: Maestro Pro, CytoView MEA Plate, Neural Module,
High-throughput assessment of barrier function using human iPSC-derived brain microvascular endothelial cells and retinal pigment epithelial cells
Poster
High-throughput assessment of barrier function using human iPSC-derived brain microvascular endothelial cells and retinal pigment epithelial cells
Author: Stacie Chvatal, Austin Passaro, Skylar Dewees, Christie Savic, Madelyn Donagan, Rebecca Fiene, Jeanie Liu, Ravi Vaidyanathan, and Coby Carlson
Product: Maestro Z, CytoView-Z Plate, Impedance Module,
Functional Analysis for iPSC-derived Three-Dimensional Models on Traditional and Novel Microelectrode Arrays
Poster
Functional Analysis for iPSC-derived Three-Dimensional Models on Traditional and Novel Microelectrode Arrays
Author: Streeter, B.W., Sullivan, D.D., Pires, J., Lindqvist, P., Passaro, A., Chvatal, S. A., Millard, D.C.
Product: Organoid MEA, Maestro Volt, Omni, Organoid Analysis Module, MEA Viability Module,
Stem Cell Reports, 9 July 2026
Publication
Induction of human pruriceptors from pluripotent stem cells via transcription factors
Author: H. Iriki, R. Hu, X. Li, E. Baljinnyam, C. Habich, I. Imanishi, L. N. Miller, K. Chegireddy, L. I. Malik, D. Yassky, R. Kübler, A. Ver Heul, K. M. Smith, P. Reinhardt, E. R. Goedken, B. S. Kim, and S. G. Marro
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Discover Nano, 06 July 2026
Publication
Experimental workflow to evaluate nanoparticles combined with photon and carbon-ion medical irradiations in spheroids
Author: F. Feghali, P. Maury, R. Hirayama, C. Dupuis, F. Savina, E. Porcel, and S. Lacombe
Product: Omni, Organoid Analysis Module,
Microbiology Spectrum, 30 June 2026
Publication
High-throughput screening system for antimycobacterial compounds using in vitro infected cells: construction and application to compounds in the Ōmura Natural Compound Library
Author: T. Takii, A. Kimishima, M. Iwatsuki, Y. Watanabe, N. Ohara, and Y. Asami
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
Axion BioSystems webinar thumbnail featuring Mike Clements, PhD, on using stem cell models, trusted NAMs, and functional assays to support drug development decisions.
Video
From Stem Cell Models to Trusted NAMs: How Functional Assays Support Drug Development Decisions
Mike Clements, PhD
Product: Maestro Pro, Maestro Edge, Maestro Volt, Maestro MEA, Cardiac Module, Neural Module, CytoView MEA Plate,
Genes & Diseases, 27 June 2026
Publication
Deleterious gain-of-function variants in RYR3 underlie developmental and epileptic encephalopathy
Author: Z. Xu, Z. Li, Y. Niu, Z. Zhou, G. Zhang, A. Ma, J. Qin, and Z. Yang
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Nature Communications, 26 June 2026
Publication
Personalized targeting of BCL2 family proteins overcomes acquired resistance to BRAF-MEK inhibitors in preclinical melanoma
Author: Y. N. Vashisht Gopal, E. de Groot, K. Loftin, B. Knighton, D. Ledesma, C. Hudgens, D. Shamsutdinova, M. Ali, Z. Ju, M. Xiao, T. Kannan, G. Fontenot, M. S. Nakazawa, M. Thomas, K. Wani, C. Stephan, P. P. Aung, L. N. Kwong, J.Roszik, R. Akbani, A. Kossenkov, V. W. Rebecca, R. J. Sullivan, M. Herlyn, and M. A. Davies
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
Mitochondrion, 19 May 2026
Publication
Role of oxidative stress in the susceptibility to mitophagy of the skin fibroblasts and iPSC-derived neurons of patients with MERRF syndrome
Author: Y. Wu, H. Tay, H. Liao, J. Yang, and Y. Wei
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
“Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation” research publication about electrical stimulation and maturation of human neuromuscular organoids.
Publication
Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation
Author: C. Moysidou, I. A. Martins, I. A. El-Shimy, I. Bicci, D. Cea, C. Bukas, I. Mekki, M. Rusu, A. Nebol, I. Lahmann, M. Piraud, E. Klotzsch, and M. Gouti
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
“Chronic Alcohol Exposure Induces Amyloid-Beta Deposition and Impaired Neuronal Maturation in Human iPSC-Derived Cortical Neurons and Cerebral Organoids” research publication about the effects of chronic alcohol exposure on amyloid-beta deposition and neuronal maturation in human cortical neurons and cerebral organoids.
Publication
Chronic alcohol exposure induces amyloid-beta deposition and impaired neuronal maturation in human iPSC-derived cortical neurons and cerebral organoids
Author: Y. Koh, J. Kim, Y. Jang, J. Han, Y. A. Rim, and J. H. Ju
Product: Maestro Edge, Neural Module, CytoView MEA Plate,