Resources

Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress

Author: K. Rhine, R. Li, H. M. Kopalle, K. Rothamel, X. Ge, E. Epstein, O. Mizrahi, A. A. Madrigal, H. Her, T. A. Gomberg, A. Hermann, J. L. Schwartz, A. J. Daniels, U. Manor, J. Ravits, R. A. J. Signer, E. J. Bennett, and G. W. Yeo

Product: Neural Module, CytoView MEA Plate,

Publication

Fibrous polyisocyanide hydrogels for 3D cell culture applications

Author: H. Yuan, K. Liu, M. J. J. van Velthoven, J. Kumari, Y. Bao, S. Rocha, and P. H. J. Kouwer

Product: Lux,

Current Research in Toxicology, 28 May 2025

Publication

Development of a workflow for in vitro on- and off-target cytotoxicity assessment of CAR T cell therapies to support first-in-human clinical trials: An orthogonal approach using hiPSC-derived cells as a surrogate for normal vital organ systems

Author: S. Price, K. G. Zindel, J. K. Overcash, E. Glaze, and S. Eldridge

Product: Maestro Z, Maestro TrayZ, Impedance Module, CytoView-Z Plate,

Publication

Adoption of microfluidic MEA technology for electrophysiology of 3D neuronal networks exposed to suborbital conditions

Author: A. E. Padilla, G. C., C. Hovell, J. Mares, V. Reumers, T. Clements, J. Rextroat, P. Gamble, B. Lumpp, and B. Joddar

Product: Maestro Edge, Neural Module, MEA Viability Module, CytoView MEA Plate,

Publication

SLC35A2 loss-of-function variants affect glycomic signatures, neuronal fate and network dynamics

Author: D. Lai, P. Sosicka, D. J. Williams, M. E. Bowyer, A. K. Ressler, S. E. Kohrt, S. J. Muron, P. B. Crino, H. H. Freeze, M. J. Boland, and E. L. Heinzen

Product: Maestro Pro, Neural Module, CytoView MEA Plate,

Publication

A hierarchy of PDZ domain scaffolding proteins clusters the Kv1 K+ channel protein complex at the axon initial segment

Author: W. Zhang, V. L. Palfini, Y. Wu, X. Ding, A. J. Melton, Y. Gao, Y. Ogawa, and M. N. Rasband

Product: Maestro Pro, Neural Module, CytoView MEA Plate,

Publication

Graphene-polymer nanofibers enable optically induced electrical responses in stem cell-derived electrically excitable cells and brain organoids

Author: E. LaMontagne, A. Savchenko, G. Gonzalez, R. Vatsyayan, B. Martin-Burgos, F. Puppo, D. Biagi, F. Papes, S. A. Dayeh, A. R. Muotri, and A. J. Engler

Product: Maestro Pro, Neural Module, Lumos, Lumos MEA Plate, CytoView MEA Plate,

Publication

In vivo assessment of iPSC-cardiomyocyte loaded auxetic cardiac patches following chronic myocardial infarction

Author: O. Brazhkina, J. H. Park, M. Brown, J. C. Walcott, J. Han, A. Turchetti, S. Roychowdhury, R. S. Prasad, M. J. Kim, I. Itzhaki, K. J. De Jesus Morales, S. J. Hollister, and M. E. Davis

Product: Maestro Edge, Cardiac Module, CytoView MEA Plate,

Publication

Establishing dorsal-ventral patterning in human neural tube organoids with synthetic organizers

Author: T. Luo, C. Liu, T. Cheng, G. Zhao, Y. Huang, J. Luan, J. Guo, X. Liu, Y. Wang, Y. Dong, Y. Xiao, E. He, R. Sun, X. Chen, J. Chen, J. Ma, S. Megason, J. Ji, and P. Xu

Product: Maestro Pro, Neural Module, CytoView MEA Plate,

Publication

A fluorescent sensor for real-time monitoring of DPP8/9 reveals crucial roles in immunity and cancer

Author: K. Weiss, Y. Agarkova, A. Zwosta, S. Hoevel, A. Himmelreich, M. Shumanska, J. Etich, G. Poschmann, B. Brachvogel, I. Bogeski, D. Mielenz, and J. Riemer

Product: Omni, Fluorescence Module,

ACS Pharmacology & Translational Science, 07 May 2025

Publication

Mechanistic Insights of a p53-Targeting Small Molecule

Author: R. J. F. Ferreira, V. Barcherini, C. Roma-Rodrigues, M. Sikorová, L. Saraiva, A. P. Leandro, P. V. Baptista, A. R. Fernandes, A. M. M. Antunes, and M. M. M. Santos

Product: Lux, Scratch Assay Module,

Publication

Cardiac Organoids on Maestro MEA

Author: Axion BioSystems

Product: Maestro Pro, Maestro Edge, Maestro Volt, Cardiac Module, CytoView MEA Plate,

Molecular Neurodegeneration, 03 May 2025

Publication

Alzheimer’s disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication

Author: X. Zhao, Y. Li, S. Zhang, A. Sudwarts, H. Zhang, A. Kozlova, M. J. Moulton, L. D. Goodman, Z. P. Pang, A. R. Sanders, H. J. Bellen, G. Thinakaran, and J. Duan

Product: Maestro Edge, CytoView MEA Plate, Neural Module,

Publication

Alzheimer’s disease patient brain extracts induce multiple pathologies in novel vascularized neuroimmune organoids for disease modeling and drug discovery

Author: Y. Ji, X. Chen, Z. Wang, C. J. Meek, J. L. McLean, Y. Yang, C. Yuan, J. Rochet, F. Liu and R. X

Product: Maestro Pro, Neural Module, CytoView MEA Plate,

Journal of Pharmaceutical Analysis, 30 April 2025

Publication

Brain organoids-on-chip for neural diseases modeling: History, challenges and trends

Author: H. Zhang, N. Huang, S. Bian, and M. Sawan

Product: Neural Module, CytoView MEA Plate,

Publication

Seizure-like behavior and hyperactivity in napb knockout zebrafish as a model for autism and epilepsy

Author: K. C. Shin, W. Hasan, G. Ali, D. Abdelrahman, T. Abuarja, L. W. Stanton, S. I. Da’as and Y. Park

Product: Maestro Pro, Neural Module, CytoView MEA Plate,

Publication

First trimester extravillous trophoblast secretes HLA class I molecules via small extracellular vesicles

Author: M. Alexandrova, D. Manchorova, I. Vangelov, A. Terzieva, V. Dimitrova, G. Mor, and T. Dimova

Product: Omni,

Current Research in Toxicology, 26 April 2025

Publication

Predicting seizure liability of small molecules using an in vitro multi-electrode array based assay coupled with modeling of brain disposition

Author: D. G. Belair, R. Kohnken, R. L. McCloud, S. Sandoval, J. Green, W. R. Buck, and J. S. Polakowski

Product: Maestro Pro, Neural Module, CytoView MEA Plate,

Publication

Cell Migration and Scratch Assays

Author: Axion BioSystems

Product: Omni, Lux,

Publication

Oncology Research

Author: Axion BioSystems

Product: Omni, Lux,