Resources
Translational Neurodegeneration, 03 June 2025
Publication
A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson’s disease cell model
Author: M. Höllerhage, L. Duan, O. W. H. Chua, C. Moebius, S. H. Bothe, K. Losse, R. Kotzur, K. Lau, F. Hopfner, F. Richter, C. Wahl-Schott, M. Bickle, and G. U. Höglinger
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Nature Neuroscience, 02 June 2025
Publication
Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress
Author: K. Rhine, R. Li, H. M. Kopalle, K. Rothamel, X. Ge, E. Epstein, O. Mizrahi, A. A. Madrigal, H. Her, T. A. Gomberg, A. Hermann, J. L. Schwartz, A. J. Daniels, U. Manor, J. Ravits, R. A. J. Signer, E. J. Bennett, and G. W. Yeo
Product: Neural Module, CytoView MEA Plate,
Nature Protocols, 30 May 2025
Publication
Fibrous polyisocyanide hydrogels for 3D cell culture applications
Author: H. Yuan, K. Liu, M. J. J. van Velthoven, J. Kumari, Y. Bao, S. Rocha, and P. H. J. Kouwer
Product: Lux,
Current Research in Toxicology, 28 May 2025
Publication
Development of a workflow for in vitro on- and off-target cytotoxicity assessment of CAR T cell therapies to support first-in-human clinical trials: An orthogonal approach using hiPSC-derived cells as a surrogate for normal vital organ systems
Author: S. Price, K. G. Zindel, J. K. Overcash, E. Glaze, and S. Eldridge
Product: Maestro Z, Maestro TrayZ, Impedance Module, CytoView-Z Plate,
OXR1 Regulates Cellular Senescence and Neuronal Aging Through Retromer-Mediated Actin Branching
Poster
OXR1 Regulates Cellular Senescence and Neuronal Aging Through Retromer-Mediated Actin Branching
Author: K. A. Wilson, T. LM McHugh, S. Alderfer, A. L. Girtle, C. Geronimo-Olvera, H. Baker, A. Das, J. Rose, J. Burton, C. G. Aguirre, E. Battistoni, M. Hady, C. Cai, I. Heckenbach, A. Afenjar, P. M. Campeau, P. L. Oliver, A. A. Gerencser, P. Kapahi, B. Schilling, and L. M. Ellerby
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
npj Microgravity, 27 May 2025
Publication
Adoption of microfluidic MEA technology for electrophysiology of 3D neuronal networks exposed to suborbital conditions
Author: A. E. Padilla, G. C., C. Hovell, J. Mares, V. Reumers, T. Clements, J. Rextroat, P. Gamble, B. Lumpp, and B. Joddar
Product: Maestro Edge, Neural Module, MEA Viability Module, CytoView MEA Plate,
Brain, 26 May 2025
Publication
SLC35A2 loss-of-function variants affect glycomic signatures, neuronal fate and network dynamics
Author: D. Lai, P. Sosicka, D. J. Williams, M. E. Bowyer, A. K. Ressler, S. E. Kohrt, S. J. Muron, P. B. Crino, H. H. Freeze, M. J. Boland, and E. L. Heinzen
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Science Advances, 23 May 2025
Publication
A hierarchy of PDZ domain scaffolding proteins clusters the Kv1 K+ channel protein complex at the axon initial segment
Author: W. Zhang, V. L. Palfini, Y. Wu, X. Ding, A. J. Melton, Y. Gao, Y. Ogawa, and M. N. Rasband
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Biomaterials, 21 May 2025
Publication
Graphene-polymer nanofibers enable optically induced electrical responses in stem cell-derived electrically excitable cells and brain organoids
Author: E. LaMontagne, A. Savchenko, G. Gonzalez, R. Vatsyayan, B. Martin-Burgos, F. Puppo, D. Biagi, F. Papes, S. A. Dayeh, A. R. Muotri, and A. J. Engler
Product: Maestro Pro, Neural Module, Lumos, Lumos MEA Plate, CytoView MEA Plate,
Biomaterials, 20 May 2025
Publication
In vivo assessment of iPSC-cardiomyocyte loaded auxetic cardiac patches following chronic myocardial infarction
Author: O. Brazhkina, J. H. Park, M. Brown, J. C. Walcott, J. Han, A. Turchetti, S. Roychowdhury, R. S. Prasad, M. J. Kim, I. Itzhaki, K. J. De Jesus Morales, S. J. Hollister, and M. E. Davis
Product: Maestro Edge, Cardiac Module, CytoView MEA Plate,
Evaluating CAR T-Cell Potency in 2D and 3D Models Using Fluorescent Live-Cell Imaging
Poster
Evaluating CAR T-Cell Potency in 2D and 3D Models Using Fluorescent Live-Cell Imaging
Author: I. Thijssen, N. Opdam-van de Laar, H. Ordutowski, D. Sullivan, and S. Meiler
Product: Omni, Fluorescence Module, Confluency Module,
Real-Time, Label-Free Assessment of HER2-targeted Antibody-Drug Conjugate Therapies
Poster
Real-Time, Label-Free Assessment of HER2-targeted Antibody-Drug Conjugate Therapies
Author: D. Sullivan, D. Califano, B. Streeter, A. Passaro, S. Chvatal, and D. Millard
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
Label-free, High-throughput Functional Assays For Evaluating The Potency And Safety Of Cell Therapies
Poster
Label-free, High-throughput Functional Assays For Evaluating The Potency And Safety Of Cell Therapies
Author: B. Streeter, D. Sullivan, D. Califano, P. Ellingson, A. Passaro, S. Chvatal, and D. Millard
Product: Maestro TrayZ, Maestro Pro, Impedance Module, MEA Viability Module, CytoView MEA Plate,
Cell Stem Cell, 14 May 2025
Publication
Establishing dorsal-ventral patterning in human neural tube organoids with synthetic organizers
Author: T. Luo, C. Liu, T. Cheng, G. Zhao, Y. Huang, J. Luan, J. Guo, X. Liu, Y. Wang, Y. Dong, Y. Xiao, E. He, R. Sun, X. Chen, J. Chen, J. Ma, S. Megason, J. Ji, and P. Xu
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Life Science Alliance, 12 May 2025
Publication
A fluorescent sensor for real-time monitoring of DPP8/9 reveals crucial roles in immunity and cancer
Author: K. Weiss, Y. Agarkova, A. Zwosta, S. Hoevel, A. Himmelreich, M. Shumanska, J. Etich, G. Poschmann, B. Brachvogel, I. Bogeski, D. Mielenz, and J. Riemer
Product: Omni, Fluorescence Module,
ACS Pharmacology & Translational Science, 07 May 2025
Publication
Mechanistic Insights of a p53-Targeting Small Molecule
Author: R. J. F. Ferreira, V. Barcherini, C. Roma-Rodrigues, M. Sikorová, L. Saraiva, A. P. Leandro, P. V. Baptista, A. R. Fernandes, A. M. M. Antunes, and M. M. M. Santos
Product: Lux, Scratch Assay Module,
Cardiac Organoid Publication Highlight
Publication
Cardiac Organoids on Maestro MEA
Author: Axion BioSystems
Product: Maestro Pro, Maestro Edge, Maestro Volt, Cardiac Module, CytoView MEA Plate,
Molecular Neurodegeneration, 03 May 2025
Publication
Alzheimer’s disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication
Author: X. Zhao, Y. Li, S. Zhang, A. Sudwarts, H. Zhang, A. Kozlova, M. J. Moulton, L. D. Goodman, Z. P. Pang, A. R. Sanders, H. J. Bellen, G. Thinakaran, and J. Duan
Product: Maestro Edge, CytoView MEA Plate, Neural Module,
Molecular Psychiatry, 02 May 2025
Publication
Alzheimer’s disease patient brain extracts induce multiple pathologies in novel vascularized neuroimmune organoids for disease modeling and drug discovery
Author: Y. Ji, X. Chen, Z. Wang, C. J. Meek, J. L. McLean, Y. Yang, C. Yuan, J. Rochet, F. Liu and R. X
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Journal of Pharmaceutical Analysis, 30 April 2025
Publication
Brain organoids-on-chip for neural diseases modeling: History, challenges and trends
Author: H. Zhang, N. Huang, S. Bian, and M. Sawan
Product: Neural Module, CytoView MEA Plate,