Marchiano S, Hsiang TY, Higashi T, Akshita Khanna A, Hans Reinecke H, Xiulan Yang X, Pabon L, Sniadecki NJ, Bertero A, Gale Jr M, Murry CE
bioRxiv, 2020
Summary:
This study demonstrated that SARS-CoV-2 readily infects and replicates within human pluripotent stem cell cardiomyoctyes (hPSC-CMs), resulting in rapid cell death. Furthermore, infected hPSC-CMs show a progressive impairment in both electrophysiological and contractile properties.
