Fibrosis rescue improves cardiac function in dystrophin-deficient mice and Duchenne patient-specific cardiomyocytes by immunoproteasome modulation

Farini A, Gowran A, Bella P, Sitzia C, Scopece A, Castiglioni E, Rovina D, Nigro P, Villa C, Fortunato F, Comi GP, Milano G, Pompilio G, Torrente Y.

Am J Pathol, 2018

Learn how Maestro MEA was used to suggest the possibility of use of the immunoproteasome as novel and clinically relevant treatment to rescue dilated cardiomyopathy in DMD patients.