Modeling cardiac fibrosis using three-dimensional cardiac microtissues derived from human embryonic stem cells

Lee MO, Jung KB, Jo SJ, Hyun SA, Moon KS, Seo JW, Kim SH, Son MY.

J Biol Eng, 2019


Follow researchers as they use Maestro MEA technology to highlight the potential of 3D cardiac microtissues as a valuable tool for manifesting and evaluating the pro-fibrotic effects of various agents, thus representing an important step forward towards an in vitro system for the prediction of drug-induced cardiac fibrosis.

Keywords: Fibrosis, cardiac disease, organoid, spheroid, microtissue, mesenchymal stem cells