Marchetto MC, Belinson H, Tian Y, Freitas BC, Fu C, Vadodaria KC, Beltrao-Braga PC, Trujillo CA, Mendes AP, Padmanabhan K, Nunez Y, Ou J, Ghosh H, Wright R, Brennand KJ, Pierce K, Eichenfield L, Pramparo T, Eyler LT, Barnes CC, Courchesne E, Geschwind DH, Gage FH, Wynshaw-Boris A, Muotri AR.
Mol Psychiatry, 2016
Summary:
Characterization of iPSC-derived neurons from individuals with autism spectrum disorder. Neuronal network deficits could be rescued by IGF-1, pointing to a potential therapeutic for some patients.
Keywords: IGF-1, autism spectrum disorder, beta-catenin
