IGF-1 treatement causes unique transcriptional response in neurons from individuals with idiopathic autism

Linker SB, Mendes APD, Marchetto MC.

Molecular Autism, 2020

Summary:

Human models for autism spectrum disorders (ASD) have established insulin-like growth factor 1 (IGF-1) as one of the most promising ASD therapeutic interventions to date. Researchers in the Marchetto lab at the Salk Institute for Biological Studies have demonstrated that IGF-1 treatment has a different impact on neurons from ASD patients compared to controls.

IGF-1 treatement causes unique transcriptional response in neurons from individuals with idiopathic autism