BioCircuit MEA

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BioCircuit 96 well bottom
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The BioCircuit microelectrode array (MEA) plates provide high-quality results together with industry-leading throughput at the lowest cost per well.

The BioCircuit MEA plate is available in 24-, 48-, and 96-well formats. Featuring low-noise recording electrodes, dedicated stimulation electrodes (24- and 48-well versions only), and on-plate spotting guides to simplify plate preparation.

Key Features

 

High quality results with industry-leading throughput.

  • Accurate cell spotting every time: BioCircuit MEA plates have on-plate spotting guides in the bottom of each well that confine the cell droplet over the recording electrodes.

  • Record high quality data: BioCircuit MEA plates provide high-quality results together with industry-leading throughput at the lowest cost per well.

  • Environmental control lids:  The evaporation-reducing lids and built-in humidity chambers help controls your cells environment.

  • Stimulate your cells: Each electrode is capable of both recording or stimulating your cells. In 24- and 48-well plates, each well contains a dedicated stimulation electrode for superior stimulation capacity and reliable capture.

BioCircuit Plate options table

* Schematic of well illustrating recording electrodes (blue), grounds (orange), and where present, a large dedicated stimulation (blue), and on-plate spotting guides (grey).

 

Overview

 

Superior droplet placement

BioCircuit MEA plates have on-plate spotting guides in the bottom of each well that confine the cell droplet over the recording electrodes. This enables more precise cell plating with less effort. Simply position the pipette between the AccuSpot features and release the droplet to ensure a perfectly centered, rounded droplet in every well.Plating cells in a small droplet centered over the electrode array will conserve cells and ensure robust electrical activity near the electrodes.

BioCircuit Droplet Placement

 

High quality MEA data

All excitable cell types perform well on the BioCircuit MEA plates, showing excellent coverage across all wells and the high signal-to-noise ratio. Track the development of electrical activity in stem cell-derived neurons or cardiomyocytes, study disease models, or examine the effects of compound treatment on excitable cells – the possibilities are endless with BioCircuit MEA plates.

 

Enhance your assay with LEAP

To complement high-quality field potential signals recorded using BioCircuit MEA plates, Axion’s patent-pending Local Extracellular Action Potential (LEAP) assay allows you to record extracellular action potential waveforms from cardiomyocytes. LEAP signals enable quantification of action potential morphology and characterization of complex repolarization irregularities such as early after depolarizations (EADs).

 

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