Concentration-response evaluation of ToxCast compounds for multivariate activity patterns of neural network function

Kosnik MB, Strickland JD, Marvel SW, Wallis DJ, Wallace K5, Richard AM, Reif DM, Shafer TJ.

Archives of Toxicology, 2019


Discover how multivariant MEA activity patterns were used to efficiently screen for neurotoxicology features and how these may be useful in predicting future responses to chemical structure features.

Keywords: toxicity, neurons, neurotoxicity, rat primary cortical neurons, environmental toxicant, multivariant analysis