Want to evaluate killing kinetics of immune cells such as natural killer (NK) cells or cytotoxic T lymphocytes (CTL) with physiologically relevant effector cell to target cell ratios? Concerned about the possible confounding effects of labeling your cells? Track immune cell-mediated killings label-free and in real-time with Maestro Z.
Endpoint cell assays limit your findings to a single snapshot in time. The Maestro Z platform, however, uses impedance-based cell analysis for real-time, continuous, label-free monitoring of your cells. Reveal the kinetics of cell-cell interactions and cell-drug responses for improved mechanistic insights of your cell model.
GPCR binding results in conformational changes and downstream responses that can be measured by impedance. These small changes often occur rapidly, but can last minutes to hours with significant physiological consequences. The Maestro Z impedance assay allows you to sensitively and continuously measure even the dynamics of cell signaling over minutes to hours without disturbing the cell biology.