Resources
Culturing hiPSC-derived excitatory neurons on MEA
Culture Protocol
Culturing Human iPSC-derived Excitatory Neurons on Microelectrode Arrays: Maestro Pro MEA
Author: Elixirgen Scientific
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System
Publication
SOX9-induced generation of functional astrocytes supporting neuronal maturation in an all-human system
Author: Neyrinck K, Van Den Daele J, Vervliet T, De Smedt J, Wierda K, Nijs M, Vanbokhoven T, D’hondt A, Planque M, Fendt S-M, Shih P-Y, Seibt F, Almenar JP, Kreir M, Kumar D, Broccoli V, Bultynck G, Ebneth A, Cabrera-Socorro A and Verfaillie C.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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News
The Next Phase of Drug Creation
Author: Meagan Parrish
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Cardiac Module,
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Publication
Impaired neuronal activity and differential gene expression in STXBP1 encephalopathy patient iPSC-derived GABAergic neurons
Author: Ichise E, Chiyonobu T, Ishikawa M, Tanaka Y, Shibata M, Tozawa T, Taura Y, Yamashita S, Yoshida M, Morimoto M, Higurashi N, Yamamoto T, Okano H, and Hirose S.
Product:
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News
Axion BioSystems’ Bioelectronic Assays Aid in the Development of Cancer Immunotherapies
Author: Axion BioSystems
Product: Maestro Z, Impedance Module, CytoView-Z Plate, Maestro ZHT, GxP Impedance Module,
Engineering hiPSC-CM and hiPSC-EC laden 3D nanofibrous splenic hydrogel for improving cardiac function through revascularization and remuscularization in infarcted heart
Publication
Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells
Author: Huang W-K, HaoWong SZ, Pather SR, Nguyen PTT, Zhang F, Zhang DY, Zhang Z, Lu L, Fang W, Chen L, Fernandes A, Su Y, Song H and Ming G-L.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2021_ieee_kim_electrophysiologicalcharacterizationofgliom
Publication
Electrophysiological characterization of glioma using a biomimetic Spheroid Model
Author: Kim KM, Tercan S, Baday M, Mahaney KB, Recht LD, Rajadas J, and Patel CB
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2021 publication pluripotent cells assessed on multielectrode array (MEA) system
Publication
A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells
Author: Chen  Y, Tristan CA, Chen L, Jovanovic VM, Malley  C, Chu P-H, Ryu S, Deng T, Ormanoglu P, Tao D, Fang Y, Slamecka  J, Hong H, LeClair  CA, Michael S, Austin CP, Simeonov  A and Singeç I.
Product: Maestro Z, Impedance Module, CytoView-Z Plate, Maestro Pro, Cardiac Module, Neural Module, CytoView MEA Plate,
Doxorubicin and cardiotoxicity
Publication
SNX17 protects the heart from doxorubicin-induced cardiotoxicity by modulating LMOD2 degradation
Author: Zhang Y, Ni L, Lin B, Hu L, Lin Z, Yang J, Wang J, Ma H, Liu Y, Yang J, Lin J, Xu L, Wu L, Shi D.
Product: Maestro Pro, Cardiac Module, BioCircuit MEA Plate,
neural organoids paper
Publication
CB1 antagonism increases excitatory synaptogenesis in a cortical spheroid model of fetal brain development
Author: Papariello A, Taylor D, Soderstrom K, and Litwa K
Product: Maestro Edge, CytoView MEA Plate, Neural Module,
2021 Principal component analysis with microelectrode array data for neural network activity
Publication
Development of an objective index, neural activity score (NAS), reveals neural network ontogeny and treatment effects on microelectrode arrays
Author: Passaro AP, Aydin O, Taher M, Saif A and Stice SL
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2021_cellres_xie_identificationofanendogenous.png
Publication
Identification of an endogenous glutamatergic transmitter system controlling excitability and conductivity of atrial cardiomyocytes
Author: Xie D, Xiong K, Su X, Wang G, Ji Q, Zou Q, Wang L, Liu Y, Liang D, Xue J, Wang L, Gao X, Gu X, Liu H, He X, Li L, Yang J, Lu Y, Peng L and Chen Y
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
2021 publication Maestro MEA comparing primate and rodent primary cortical neurons
Publication
Differential development and electrophysiological activity in cultured cortical neurons from the mouse and cynomolgus monkey
Author: Zhang X-Y, Li J, Li C-J, Lin Y-Q, Huang C-H, Zheng X, Song X-C, Tu Z-C, Li X-J, and Yan S.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Axion Bio Cancer Immunotherapy Application Note
Application Note
Quantifying Proliferation and Cytotoxicity of Suspension Human Cancer Cell Lines Using the Maestro Z
Author: Axion BioSystems
Product: Maestro ZHT, Impedance Module, CytoView-Z Plate, Maestro Z, GxP Impedance Module,
Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy
Publication
Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy
Author: Negraes PD, Trujillo CA, Yu N-K, Wu W, Yao H, Liang N, Lautz JD, Kwok E, McClatchy D, Diedrich J, de Bartolome SM, Truong J, Szeto R, Tran T, Herai RH, Smith SEP, Haddad GG, Yates JR and Muotri AR.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
What is in vitro potency assay for cancer immunotherapy
Video
In vitro potency assays for cancer immunotherapy
Axion BioSystems
Product: Maestro ZHT, CytoView-Z Plate, GxP Impedance Module, Maestro Z, Impedance Module, Impedance Automation Module,
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News
Axion BioSystems Announces Formation of Scientific Advisory Board
Author: Axion BioSystems
Product: Maestro Pro, Maestro Edge, Maestro Z, Maestro ZHT,
2021 publication altered neuronal support with bipolar disorder
Publication
Altered neuronal support and inflammatory response in bipolar disorder patient-derived astrocytes
Author: Vadodaria KC, Mendes APD, Mei A, Racha V, Erikson G, Shokhirev MN, Oefner R, Heard KJ, McCarthy MJ, Eyler L, Kelsoe JR, Santos R, Marchetto MC, and Gage FH.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies
Author: Chour T, Tian L, Lau E, Thomas D, Itzhaki I, Malak O, Zhang JZ, Qin X, Wardak M, Liu Y, Chandy M, Black KE, Lam MP, Neofytou E, and Wu JC.
Product: Maestro Pro, Cardiac Module, BioCircuit MEA Plate,
2021 Publication cardiac laminopathy on MEA system
Publication
Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy
Author: Bertero A, Fields PA, Smith AST, Leonard A, Beussman K, Sniadecki NJ, Kim D, Tse H, Pabon L, Shendure J, Noble WS, Murry CE
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,