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Axion News
News
Axion BioSystems Announces BioLamina Distribution Agreement to Support Organoid Research
Author: Axion BioSystems
Product: Axion MEA, Organoid MEA, MEA Creator Kit,
Nature Genetics, 14 August 2026
Publication
PLCG2 downregulation impairs synaptic function and increases Alzheimer’s disease hallmarks in neuronal cultures
Author: A. Coulon, F. Rabiller, M. Takalo, A. Roy, A. Pelletier, H. Martiskainen, D. Siedlecki-Wullich, N. Lannette-Weimann, N. Majerníková, A. Grenon, V. Gao, A. Erhardt, A. Pernodet, M. Lemaire, F. Limoge, P. Walle, T. Mendes, K. Guyot, C. Lemeu, L. Carvalho, A. R. M. de Farias, M. Hulsman, C. Najdek, A. Freire-Regatillo, O. Saha, P. Amouyel, C. Charbonnier, J. Deleuze, O. Dols-Icardo, H. Jeskanen, R. Willman, T. Kuulasmaa, M. Kurki, J. Hardy, S. Heikkinen, H. Holstege, P. Mäkinen, G. Nicolas, S. Mead, M. Wagner, A. Ramirez, T. Rauramaa, A. Palotie, R. Sims, H. Soininen, J. van Swieten, J. Williams, C. Bellenguez, C. Gelle, E. Lambert, M. R. Costa, J. TCW, E. Glaab, A. Ayral, F. Demiautte, B. Grenier-Boley, M. Muntaner, D. Eberlé, S. Deforges, J. T. Haas, D. Kilinc, C. Mulle, J. Chapuis, M. Hiltunen, J. Dumont, and J. Lambert
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Advanced Science, 12 August 2026
Publication
Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia
Author: P. Ni, Q. Zhang, Y. Jiang, H. Yao, C. Zhou, X. Tian, S. Gao, J. Zhao, X. Ren, N. Xu, M. Fu, L. Zhao, X. Qi, X. Yu, W. Guo, S. Chung, F. Guo, and T. Li
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Nature Communications, 12 August 2026
Publication
Inflammatory neuropathy in mouse and primate models of colorectal cancer
Author: C. M. Gaffney, A. M. Casaril, I. Mahmud, B. Wei, Y. Jiang, N. T. Fiore, J. Liu, K. M. Valadez, E. A. Kolb, F. R. Cherry, L. Shi, K. Dunner Jr., P. L. Lorenzi, S. R. Reiken, P. M. Grace, R. Mahalingam, T. A. Guise, C. L. Hodo, and A. J. Shepherd
Product: Maestro Edge, Neural Module, MEA Viability Module, CytoView MEA Plate,
Advanced Materials, 10 August 2026
Publication
Engineering Pluripotent Stem Cells-Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro-Topographical Cues
Author: H. Sharma, J. Lim, W. Kim, Y. J. Kim, D. Kim, S. Lee, C. Park, S. Rhee, S. Kuttapan, J. Ha, S. W. Park, K. Kim, N. L. Jeon, S. Park, Y. Choung, and J. Kim
Product: Axion MEA, Neural Module, CytoView MEA Plate,
LEAP: Scalable cardiac action potential electrophysiology​
Video
LEAP™: Scalable cardiac action potential electrophysiology​
Axion BioSystems
Product: Axion MEA, Maestro Edge, Maestro Pro, Maestro Volt, Cardiac Module, CytoView MEA Plate,
CNS Neuroscience & Therapeutics, 03 August 2026
Publication
CLRN1 Variants in Müller Cells Cause Mitochondrial Dysfunction in USH3A Retinal Organoids
Author: R. Zhang, X. Ji, H. Yu, J. Xu, Y. Wang, P. Sun, Y. Wang, Y. Tang, Z. Zhan, Y. Jiao, D. Shan, P. Lin, D. Wang, Y. Zhao, X. Liu, C. Yan, J. Li, M. Li, F. Liu, and S. Hou
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Small Science, 31 July 2026
Publication
Injectable Artificial Photoreceptors: STEM Cell Functional Integration and in vivo Electrophysiological Validation in Retinal Degeneration Models
Author: A. Izadian, A. Torkashvand, B. A. McCall, Y. Gao, C. M. Taylor, F. K. Hafshejani, A. Das, M. L. Surma, S. Gong, and A. R. Hajrasouliha
Product: Maestro Edge, Lumos, Lumos MEA Plate, Neural Module,
Toxicological Sciences, 30 July 2026
Publication
Building structure activity relationships to avoid toxicity due to unwanted central nervous system ion channel activity
Author: L. A. K .Zolkiewski, K. L. Rockley, R. A. Roberts, H. G. Jennings, M. Maizières, K. Jones, J. L. McDonagh, K. Newman, E. J. Griffen, J. E. Stacey, and M. J. Morton
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
FENS2026_NeuralNetworkFormationAssay
Poster
Development of a Neural Network Formation Assay for Primary and iPSC-Derived Neural Models
Author: Sullivan, D.D., Ellingson, P., Pires, J., Lindqvist, P., Barnes, S., Streeter, B.W., Passaro, A., Millard, D.C.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Culture Protocol - Cardiac Organoids CytoView MEA
Culture Protocol
Cardiac Organoids on CytoView MEA Protocol
Author: Axion BioSystems
Product: Axion MEA, Cardiac Module, CytoView MEA Plate,
Nature Communications, 22 July 2026
Publication
Structural insights enable drug discovery for the neuronal NBCn2 carbonate transporter
Author: S. Yang, Y. Zhao, S. Vatansever, G. Zilberg, M. J. Capper, J. Zhang, J. Stamos, K. Hutchinson, A. L. Warren, A. C. Stone, A. Abbassi, E. Purisic, L. Ho, A. Li, J. Dai, A. Schlessinger, B. Zhang, and D. Wacker
Product: Axion MEA, Neural Module, CytoView MEA Plate,
Science Translational Medicine, 22 July 2026
Publication
Modulating the VIP-VIPR pathway reprograms CAR T cells for superior antitumor efficacy in preclinical cancer models
Author: H. K. Lin, D. A. Blake, R. Freeman, Y. Chen, J. Kim, A. M. Johnson, K. Wells, A. Mudigonda, W. Liu, P. Yadav, F. Zeng, A. Muhuri, K. Min, S. Sarkar, Y. Wang, S. Goyal, R. C. Roberts, E. Christensen, A. B. Ward, B. Heller, P. Chun, J. Dougan, C. C. Porter, B. G. Barwick, C. M. Paulos, L. Yang, A. Patgiri, S. N. Thomas, E. K. Waller, and S. Rafiq
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
“Scalable Hypothalamic Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic Disorders” research publication about generating hypothalamic neurons from human pluripotent stem cells for metabolic disease modeling.
Publication
Scalable hypothalamic neuron differentiation from human pluripotent stem cells suitable for modeling metabolic disorders
Author: V. M. Jovanovic, N. Narisu, L. L. Bonnycastle, D. Castellano, S. Ryu, R. Tharakan, K. T. Mesch, Q. Chen, F. M. B. Erol, H. J. Glover, T. Yan, N. Sinha, C. Sen, S. Yang, D. Blivis, D. F. Bennett, G. Rosales-Soto, J. Inman, P. Ormanoglu, C. A. LeClair, N. D. Shaw, M. Xia, M. Schneider, E. O. Hernandez-Ochoa, M. R. Erdos, A. Simeonov, S. Chen, F. S. Collins, C. A. Doege, and C. A. Tristan
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
NeuroToxicology, 13 July 2026
Publication
Detection of seizurogenic compounds in human and rat neurons in vitro: A multi-laboratory, multi-model assessment
Author: R. Roberts, K. Blinova, C. Carlson, M. Cato, K. Czysz, T. K. Feaster, X. Han, Y. Ishibashi, Y. Kanda, M. Kreir, P. Levesque, N. Miyamoto, J. B. Pierson, T. J. Shafer, S. Schachtele, C. J. Strock, T. Yoshinaga, and I. Suzuki
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Development and Functional Assessment of iPSC-derived Endothelial Cells using a Novel Non-Invasive Workflow
Poster
Development and Functional Assessment of iPSC-derived Endothelial Cells using a Novel Non-Invasive Workflow
Author: Barnes, S., Sullivan, D.D., Ellingson, P., Streeter, B.W., Passaro, A., Millard, D.C.
Product: Omni, Scratch Assay Module, Maestro Z, Impedance Module, CytoView-Z Plate, iPSC Module, Fluorescence Module,
Establishing a functional standard for hiPSC-neural models used to screen for seizure liability with the multielectrode array (MEA) assay
Poster
Establishing a functional standard for hiPSC-neural models used to screen for seizure liability with the multielectrode array (MEA) assay
Author: Mike Clements, Matthew Cato, Khuram W Chaudhary, Stacie Chvatal, Annie Delaunois, Parker Ellingson, Steve Fiene, Catherine Garrison, Mohamed Kreir, Norimasa Miyamoto, Katie Newman, Bumpei Noda, Kimberly L Rockley, Leandro Royer, Timothy J
Shafer, Christopher Strock, Ikuro Suzuki, Anke M Tukker, Remco HS Westerink, Takashi Yoshinaga, and Louisa AK Zolkiewski
Product: Maestro Pro, CytoView MEA Plate, Neural Module,
High-throughput assessment of barrier function using human iPSC-derived brain microvascular endothelial cells and retinal pigment epithelial cells
Poster
High-throughput assessment of barrier function using human iPSC-derived brain microvascular endothelial cells and retinal pigment epithelial cells
Author: Stacie Chvatal, Austin Passaro, Skylar Dewees, Christie Savic, Madelyn Donagan, Rebecca Fiene, Jeanie Liu, Ravi Vaidyanathan, and Coby Carlson
Product: Maestro Z, CytoView-Z Plate, Impedance Module,
Functional Analysis for iPSC-derived Three-Dimensional Models on Traditional and Novel Microelectrode Arrays
Poster
Functional Analysis for iPSC-derived Three-Dimensional Models on Traditional and Novel Microelectrode Arrays
Author: Streeter, B.W., Sullivan, D.D., Pires, J., Lindqvist, P., Passaro, A., Chvatal, S. A., Millard, D.C.
Product: Organoid MEA, Maestro Volt, Omni, Organoid Analysis Module, MEA Viability Module,
Stem Cell Reports, 9 July 2026
Publication
Induction of human pruriceptors from pluripotent stem cells via transcription factors
Author: H. Iriki, R. Hu, X. Li, E. Baljinnyam, C. Habich, I. Imanishi, L. N. Miller, K. Chegireddy, L. I. Malik, D. Yassky, R. Kübler, A. Ver Heul, K. M. Smith, P. Reinhardt, E. R. Goedken, B. S. Kim, and S. G. Marro
Product: Maestro Pro, Neural Module, CytoView MEA Plate,