Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Nav1.7 mutation I234T

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Yang Y, Adi T, Effraim PR, Chen L, Dib-Hajj SD, Waxman SG.

Br J Pharmacol, 2018

Summary:

MEA is used to assess the effects of carbamazepine on Nav1.7 mutants in a case of inherited erythromelagia.

Keywords: dorsal root ganglion, pain, DRG, carbamazepine, burning man syndrome, erythromelagia, Nav1.7

 
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