Enhanced drug internalization and therapeutic efficacy of PEGylated nanoparticles by one-step formulation with anti-mPEG bispecific antibody in intrinsic drug-resistant breast cancer

Cheng YA, Chen IJ, Su YC, Cheng KW, Lu YC, Lin WW, Hsieh YC, Kao CH, Chen FM, Roffler SR, Cheng TL.

Biomater Sci, 2019

Summary: 

Discover how Axion Muse technology aided researchers in evaluating the toxicity of αHER2/PLD in human cardiomyocytes and mice.

Keywords: breast cancer, cardiotoxicity, HER2, doxorubicin, human epidermal growth factor receptor 2, methoxy-polyethylene glycol, mPEG, cytotoxicity