Characterization of calcium responses and electrical activity in differentiating mouse neural progenitor cells in vitro

de Groot MW, Dingemans MM, Rus KH, de Groot A, Westerink RH.

Toxicology Science, 2013

Summary:

Multielectrode arrays were used to confirm the functional intercellular signalling pathways within 1-2 weeks of differentiation by mouse neural progenitor cells.  Therefore confirming this in vitro model to evaluate developmental neurotoxicity.

Keywords: differentiating mouse neural progenitor cells, developmental neurotoxicity testing

Characterization of calcium responses and electrical activity in differentiating mouse neural progenitor cells in vitro