ABBV-712-induced cardiac pathology in rats is related to off-target-driven acute vasodilation, tachycardia, and increased cardiac contractility

Authors: Rebecca Kohnken, Stacey Fossey, Wayne R Buck, Jason Segreti, Jessica Treadway, Jonathon Green, Yevgeniya E Koshman, Mark Zafiratos, Scott Mittelstadt, Eric Blomme, and Charles M Foley

Toxicological Sciences, 12 April 2025