Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene

X. Shawn Liu, Hao Wu, Marine Krzisch, Angela Cacace, Richard A. Young, Rudolf Jaenisch

Cell, 2018

Summary:

Liu et al. demonstrate how fragile X syndrome neurons can be rescued by CRISPR-mediated DNA methylation editing of the FMR1 gene using the Maestro MEA system.