Neural Organoid Activity Assay

The promise of organoids

Three-dimensional induced pluripotent stem cell (iPSC)- derived in vitro cell models, commonly referred to as spheroids, organoids, or “mini-brains”, more accurately recapitulate the multicellular organization and structure of in vivo tissues when compared to traditional monolayer cell cultures. Recent trends in developmental biology and disease-in-a-dish modeling modeling highlight the value of re-creating in vivo micro-environments. Assessing the function of 3D models is vital for understanding disease models, drug discovery, and drug safety