Axion MEA
Axion BioSystems makes the world’s most advanced MEA platforms — offering unmatched throughput, resolution, flexibility, and performance.
Microelectrode array (MEA) technology reveals how living cells function in real time—noninvasively and without labels. At Axion BioSystems, MEA is moving beyond conventional electrophysiology, combining established multiwell assays with higher-density measurement and new forms of spatial insight. Explore what MEA can reveal across neural, cardiac, and advanced cell models, compare available approaches, and find the Axion MEA platform that fits your research.
Key Features
What MEA reveals
What cells look like does not always reveal how they function. MEA and HD-MEA record signals produced by electrically active cells, revealing when cells are active, how that activity is coordinated, and how it changes over time. MEA captures function across cell populations and networks, while HD-MEA adds the spatial resolution needed to investigate electrical activity at the level of individual cells. Because both approaches are label-free and noninvasive, researchers can repeatedly measure the same cultures as they develop, respond, and recover—capturing dynamic biology that endpoint assays can miss.
Functional activity
Measure neural firing, cardiac beating, field potentials, and other indicators of cellular function in real time.
Network behavior
Quantify bursting, synchrony, connectivity, conduction, and coordinated activity across cells and networks.
Response over time
Track maturation, disease progression, treatment response, toxicity, and recovery in one living culture.
Redefining what MEA can do
Axion BioSystems’ MEA goes beyond conventional electrophysiology. By combining high-throughput and high-definition MEA with electrical imaging, we are connecting scalable functional measurement with high-resolution spatial mapping and label-free views of cellular change. Together, these approaches broaden what researchers can learn from living biology—and push the boundaries of what MEA can do.
MEA
Measure functional activity across established, scalable multiwell assays.
HD-MEA
Map activity and signal propagation with greater spatial and cellular detail.
Electrical imaging
Follow cellular coverage and morphology, organization, and response across space and time—without labels.
• Featured platform
Synexus: The next evolution of MEA.
Synexus expands what an MEA platform can be. The next-generation, functional cell analysis platform is the only system to bring proven MEA, HD-MEA, and high-content electrical imaging together. Synexus carries established assays forward while opening new ways to map activity, add spatial context, and follow living biology over time.
Scale and detail in one platform
Perform scalable multiwell assays and high-density measurement without choosing between throughput and resolution.
Designed around living biology
Maintain stable culture conditions, protect signal quality, and coordinate measurement and stimulation across the experiment.
Built to evolve with your research
Start with the workflows labs rely on today and expand into new measurements, formats, and applications as your research advances.
Overview
The complete Axion MEA ecosystem
Choose the measurement capabilities and throughput that fit your research, from established multiwell MEA workflows to high-density and multimodal analysis.
Synexus
A next-generation, high-throughput platform combining MEA, HD-MEA, and electrical imaging.
Maestro Pro
A high-throughput MEA platform offering maximum flexibility across all MEA modules and plate types.
Maestro Edge
A versatile medium-throughput platform combining MEA and impedance for a broad range of experiments.
Maestro Volt
An accessible MEA system for labs focused on core neural or cardiac electrophysiology.
A successful MEA experiment takes more than a measurement system. Axion brings instruments, software, consumables, stimulation, automation, imaging, and scientific expertise together as an integrated ecosystem for building, running, and expanding functional live-cell assays.
Plates for your biology
Work across neural, cardiac, organoid, and other advanced models with plate formats and electrode configurations designed around different experimental needs.
Software and analysis
Turn complex signals into meaningful biological insight with application-focused acquisition, analysis, visualization, and reporting tools.
Connected live-cell workflows
Combine functional MEA data with live-cell imaging and other complementary measurements to build a more complete view of living biology.
Stimulation and automation
Add optical stimulation, automate high-throughput workflows, and coordinate measurements across increasingly complex experiments. Electrical stimulation is included with all platforms.
Scientific expertise and support
Draw on Axion’s experience developing assays, optimizing workflows, interpreting data, and helping researchers move from experimental question to reliable result.
Proven MEA expertise
Axion’s MEA expertise is built on years of partnership with researchers translating complex electrical signals into meaningful biological insight. From assay development and experimental design to analysis and interpretation, our platforms and scientists support functional research across academic, biotechnology, pharmaceutical, and contract research laboratories worldwide.
Peer-reviewed publications
A growing body of independent research spanning neuroscience, cardiac research, drug discovery, safety, disease modeling, and advanced cell models.
MEA systems installed
Supporting functional live-cell research in academic and pharmaceutical laboratories around the world.
Top pharma safety groups
Leading organizations rely on Axion’s MEA systems for predictive, human-relevant cardiac and neural safety research.
Expertise beyond the instrument
Experienced applications scientists help researchers develop assays, optimize workflows, interpret complex data, and move confidently from experimental question to reliable result.
Find the right
MEA solution
Your application, cell model, throughput, and measurement goals all shape the right approach. Our MEA experts can help you compare capabilities, explore workflows, and identify the platform and configuration that best supports your research.
What happens next
1
Tell us about your research
2
Connect with an Axion expert
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Explore the right system or demo
Discover what’s possible with MEA
Axion’s MEA expertise is built on years of partnership with researchers translating complex electrical signals into meaningful biological insight. From assay development and experimental design to analysis and interpretation, our platforms and scientists support functional research across academic, biotechnology, pharmaceutical, and contract research laboratories worldwide.
MEA resources and learning
Whether you are new to MEA or advancing an established assay, explore educational content and practical guidance to support your research. Learn the fundamentals, compare measurement approaches, develop workflows, and see how researchers are applying MEA across living cell models.
Learn the fundamentals Understand how MEA works, what it measures, and how functional data can complement traditional biological endpoints.
Compare measurement approaches Discover the differences between classic MEA and HD-MEA—and where each approach fits your experimental goals.
Develop your assay Access protocols, application notes, technical guides, and practical resources for building reliable neural, cardiac, and advanced cell-model workflows.
See MEA in action Hear from scientists and application experts as they explore how MEA is used across discovery, disease modeling, and safety research.
Learn the fundamentals
Understand how MEA works, what it measures, and how functional data can complement traditional biological endpoints.
Compare measurement approaches
Discover the differences between standard MEA and HD-MEA—and where each approach fits your experimental goals.
Develop your assay
Access protocols, application notes, technical guides, and practical resources for building reliable neural, cardiac, and advanced cell-model workflows.
See MEA in action
Watch webinars, examine application data, and explore peer-reviewed research demonstrating MEA across discovery, disease modeling, and safety applications.
