Immune Cells

Description

Immune cell-mediated killing of cancer cells is a promising therapy that utilizes cells from both the adaptive and innate immune system, such as natural killer (NK) cells, cytotoxic T cells, B lymphocytes, etc.  Axion BioSystems' Maestro Z, ZHT, Pro, and Edge systems capture the kinetics of immune interactions with cancer cells for better mechanistic understanding without the time- and cost-intensive process of repeating multiple endpoint assays.

Review our resources on this topic from application notes to free webinars.

Neuron, 23 December 2024
Publication
A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion
Author: A. Flury, L. Aljayousi, H. Park, M. Khakpour, J. Mechler, S. Aziz, J. D. McGrath, P. Deme, C. Sandberg, F. G. Ibáñez, O. Braniff, T. Ngo, S. Smith, M. Velez, D. M. Ramirez, D. Avnon-Klein, J. W. Murray, J. Liu, M. Parent, S. Mingote, N. J. Haughey, S. Werneburg, M. Tremblay, and P. Ayata
Product: Maestro Pro, CytoView MEA Plate, Neural Module,
Animals, 2 October 2024
Publication
Investigating the IgM and IgG B Cell Receptor Repertoires and Expression of Ultralong Complementarity Determining Region 3 in Colostrum and Blood from Holstein-Friesian Cows at Calving
Author: T. E. Altvater-Hughes, H. P. Hodgins, D. C. Hodgins, C. A. Bauman, M. A. Paibomesai, and B. A. Mallard
Product: Exact FL, Cell Counting Module,
American Journal of Transplantation, 11 August 2024
Publication
Deficiency in the mitophagy mediator Parkin accelerates murine skin allograft rejection
Author: K. M. Wragg, M. J. Worley, J. C. Deng, M. Salmon, and D. R. Goldstein
Product: Exact FL, Cell Counting Module,
TrayZ Technical Note
Application Note
Multiplate cell-based assays with Maestro TrayZ for cytotoxicity and potency
Author: D. Sullivan & D. Millard
Product: Maestro TrayZ, Impedance Module, CytoView-Z Plate,
App Note glycostem NK cell and glioblastoma
Application Note
Quantifying NK-mediated Cytolysis of Glioblastoma in vitro with Maestro Z
Author: Axion BioSystems (data provided by Glycostem Therapeutics)
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
Glioblastoma Therapies
Publication
GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma
Author: T. Gargett, L. Ebert, N. Truong, P. Kollis, K. Sedivakova, W. Yu, E. Yeo, N. Wittwer, B. Gliddon, M. Tea, R. Ormsby, S. Poonnoose, J. Nowicki, O. Vittorio, D. Ziegler, S. Pitson and M. Brown
Product: Maestro Z, CytoView-Z Plate,
Scientific Reports, 17 June 2022
Publication
Functional HLA‑C expressing trophoblast spheroids as a model to study placental–maternal immune interactions during human implantation
Author: M. Alexandrova, D. Manchorova, Y. You, G. Mor, V. Dimitrova and T. Dimova
Product: Omni,
thumbnail of publication
Publication
Locally secreted BiTEs complement CAR T cells by enhancing killing of antigen heterogeneous solid tumors
Author: Yin Y, Rodriguez JL, Li N, Thokala R, Nasrallah MP, Hu L, Zhang L, Zhang JV, Logun MT, Kainth D, Haddad L, Zhao Y, Wu T, Johns EX, Long Y, Liang H, Qi J, Zhang X, Binder ZA, Lin Z, O'Rourke DM.
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
Axion Bio App Note TEER
Application Note
TEER with Maestro Z
Author: Axion BioSystems
Product: Maestro Z, Impedance Module, CytoView-Z Plate, Maestro Edge, Maestro Pro, Impedance Automation Module,
Axion Bio App Note Cytotoxicity
Application Note
Tracking the Dynamics of Cytotoxicity in Real-Time with the Maestro Z Impedance Assay
Author: Axion BioSystems
Product: Maestro Z, Impedance Module, CytoView-Z Plate, Maestro Edge, Maestro Pro, Impedance Automation Module,