Phenotypic drug screening has recently produced more first-in-class drugs than any other method, including target-based approaches. With the Maestro, high-throughput electrophysiology assessment of a functioning cell network provides a innovative approach to drug discovery. Information on how drugs affect electrically active cells can be generated rapidly and directly on the benchtop without advanced training in electrophysiology.
Discovery screening requires high-throughput and high volume for both experiments and data analysis. Axion’ commitment to drug discovery applications includes launching a number of industry-first products. The 96-well MEA plate advances high throughput applications through high well count combined with robust data collection from 8 electrodes per well. To facilitate high volume, Axion has introduced Maestro APEX, a benchtop workstation that automates every facet of Maestro experiments from cell culture through dosing, allowing you to screen more plates and more compounds faster than ever. Software tools such as the AxIS Metric Plotting Tool make data analysis simple, allowing you to see the effects of drug candidates across the plate with a simple click of the mouse.