Resources
2020 Neuron Wang Publication on therapeutics for Alzheimers Disease
Publication
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease
Author: Wang M, Li A, Sekiya M, Beckmann ND, Quan X, Schrode N, Fernando MB, Yu A, Zhu L, Cao J, Lyu L, Horgusluoglu E, Wang Q, Guo L, Wang, Y-S, Neff R, Song W-M, Wang E, Shen Q, Zhou X, Ming C, Ho S-M, Vatansever S, Kaniskan HU, Jin J, Zhou M-M, Ando K, Ho L, Slesinger PA, Yue Z, Zhu J, Katsel P, Gandy S, Ehrlich ME, Fossati V, Noggle S, Cai D, Haroutunian V, Iijima KM, Schadt E, Brennand KJ, Zhang B.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Plos Biology Bauer
Publication
Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C
Author: Bauer L, Manganaro R, Zonsics B, Hurdiss DL, Zwaagstra M, Donselaar T, Welter NGE, van Kleef RGDM, Lopez ML, Bevilacqua F, Raman T, Ferla S, Bassetto M, Neyts J, Strating JRPM, Westerink RHS, Brancale A, van Kuppeveld FJM.
Product: Maestro Pro, Neural Module, BioCircuit MEA Plate,
2020 mechanisms of QT prolongation on MEA system
Publication
Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block
Author: Tran PN, Sheng J, Randolph AL, Baron CA, Thiebaud N, Ren M, Wu M, Johannesen L, Volpe DA, Patel D, Blinova K, Strauss DG and Wu WW.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
2020 publication neuronal medium optimized for optogenetics
Publication
BrainPhys neuronal medium optimized for imaging and optogenetics in vitro
Author: Zabolocki M, McCormack K, van den Hurk M, Milky B, Shoubridge AP, Adams R, Jenne Tran J, Mahadevan-Jansen A, Reineck P, Thomas J, Hutchinson MR, Mak CKH, Añonuevo A, Chew LH, Hirst AJ, Lee VM, Knock E and Bardy C.
Product: Maestro Pro, Neural Module, Lumos MEA Plate, Lumos,
2020 publication on epilepsy and multielectrode array system
Publication
An epilepsy‐associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model
Author: Ahn LY, Coatti GC, Liu J, Gumus E, Schaffer AE, Miranda HC.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Publication on methadone and cortical organoids on MEA system
Publication
Methadone interrupts neural growth and function in human cortical organoids
Author: Yao H, Wu W, Cerf I, Zhao HW, Wang J, Negraes PD, Muotria AR, Haddad GG.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 publication on reduced gaba on neuronal excitability
Publication
Reduced GABAergic Neuron Excitability, Altered Synaptic Connectivity, and Seizures in a KCNT1 Gain-of-Function Mouse Model of Childhood Epilepsy
Author: Shore AN, Colombo S, Tobin WF, Petri S, Cullen ER, Dominguez S, Bostick CD, Beaumont MA, Williams D, Khodagholy D, Yang M, Lutz CM, Peng Y, Gelinas JN, Goldstein DB, Boland MJ, Frankel WN, Weston MC.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 EFSA publication on in vitro neurotoxicity
Publication
Establishment of an a priori protocol for the implementation and interpretation of an in‐vitro testing battery for the assessment of developmental neurotoxicity
Author: EFSA: European Food Safety Authority
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Toxicology hiPSC-derived neuronal co-culture for seizure on MEA
Publication
Applicability of hiPSC-derived neuronal co-cultures and rodent primary cortical cultures for in vitro seizure liability assessment
Author: Tukker AM, Wijnolts FMJ, de Groot A, Westerink RHS
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Journal of Industrial and Engineering Chemistry, 16 October 2020
Publication
Production of elastin-like recombinamer-based nanoparticles for docetaxel encapsulation and use as smart drug-delivery systems using a supercritical anti-solvent process
Author: R. Vallejo, J. Gonzalez-Valdivieso, M. Santos, S. Rodriguez-Rojo, and F.J. Arias
Product: Omni,
2020 publication toxicology MEA and neurotransmission
Publication
Synthetic cannabinoids enhanced ethanol-induced motor impairments through reduction of central glutamate neurotransmission
Author: Funada M, Takebayashi-Ohsawa M, Tomiyama K.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Hyaluronan in neuronal networks and cortical organoids with MEA assay
Publication
Hyaluronan regulates synapse formation and function in developing neural networks
Author: Wilson E, Knudson W, and Newell-Litwa K.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
thumbnail of publication
Publication
Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events
Author: Ballouz S, Mangala MM, Perry MD, Heitmann S, Gillis JA, Hill AP, and Vandenberg JI.
Product: Maestro Edge, Cardiac Module,
2020 Paper on neuronal activity by microglia with maestro pro
Publication
Negative feedback control of neuronal activity by microglia
Author: Badimon A, Strasburger HJ, Ayata P, Chen X, Nair A, Ikegami A, Hwang P, Chan AT, Graves SM, Uweru JO, Ledderose C, Kutlu MG, Wheeler MA, Kahan A, Ishikawa M, Wang Y-C, Loh Y-WE, Jiang JX, Surmeier DJ, Robson SC, Junger WG, Sebra R, Calipari ES, Kenny PJ, Eyo UB, Colonna M, Quintana FJ, Wake H, Gradinaru V and Schaefer A
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Brain patient-derived neurons and epilepsy
Publication
Variant-specific changes in persistent or resurgent sodium current in SCN8A-related epilepsy patient-derived neurons
Author: Tidball AM, Lopez-Santiago LF, Yuan Y, Glenn TW, Margolis JL, Walker JC, Kilbane EG, Miller CA, Bebin EM, Perry MS, Isom LL, Parent JM
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Circulation Hanses inotronic crispr paper
Publication
Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome–Associated Cardiomyopathy
Author: Hanses U, Kleinsorge M, Roos L, Yigit G, Li Y, Barbarics B, El-Battrawy I, Lan H, Tiburcy M, Hindmarsh R, Lenz C, Salinas G, Diecke S, Müller C, Adham I, Altmüller J, Nürnberg P, Paul T, Zimmermann W-H, Hasenfuss G, Wollnik B, Cyganek L.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
2020_naturecommun_zaifeiriou_developmentalgabapolarityswitch
Publication
Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids
Author: Zafeiriou M-P, Bao G, Hudson J, Halder R, Blenkle A, Schreiber M-K, Fischer A, Schild D, Zimmermann W-H.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2020 Day lab paper on cocaine addiction
Publication
Regulation of dopamine-dependent transcription and cocaine action by Gadd45b
Author: Zipperly ME, Sultan FA, Graham G-E, Brane AC, Simpkins NA, Carullo NVN, Ianov L, Day JJ.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 SLAS Discovery assessment of proarrythmic drug on MEA system
Publication
Assessment of Drug Proarrhythmic Potential in Electrically Paced Human Induced Pluripotent Stem Cell–Derived Ventricular Cardiomyocytes Using Multielectrode Array
Author: Bai S, Pei J, Chen K, Zhao Y, Cao H, Tian L, Ma Y and Dong H.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
2020 Cytoskeleton adhesion on MEA system
Publication
Inhibition of focal adhesion kinase increases myofibril viscosity in cardiac myocytes
Author: Taneja N, Bersi MR, Rasmussen ML, Gama V, Merryman WD, Burnette DT
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,