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Differentiation and on axon-guidance chip culture of human pluripotent stem cell-derived peripheral cholinergic neurons for airway neurobiology studies

Author: Goldsteen PA, Sabogal Guaqueta AM, Mulder PPMFA, Bos IST, Eggens M, Van der Koog L, Soeiro JT, Halayko AJ, Mathwig K, Kistemaker LEM, Verpoorte EMJ, Dolga AM, Gosens R

Product: Maestro Pro, Neural Module, CytoView MEA Plate,

Publication

Acute, sub-chronic and chronic exposures to TiO2 and Ag nanoparticles differentially affects neuronal function in vitro

Author: Gerber LS, Heusinkveld HJ, Langendoen C, Stahlmecke B, Schins RPF, Westerink RHS

Product: Maestro Edge, Neural Module, CytoView MEA Plate,

Publication

Generation of human iPSCs derived heart organoids structurally and functionally similar to heart

Author: Lee S-G, Kim Y-J, Son M-Y, Oh M-S, Kim J, Ryu B, Kang K-R, Baek J, Chung G, Ho D, Woo, Kim C-Y, Chung C

Product: Maestro Edge, Cardiac Module, CytoView MEA Plate,

Publication

Human fetal membrane-mesenchymal stromal cells generate functional spinal motor neurons in vitro

Author: Gaggi G, Di Credico A, Guarnieri S, Mariggio MA, Ballerini P, Di Baldassarre A, Ghinassi B

Product: Maestro Edge, Neural Module, CytoView MEA Plate,

Publication

Wide spectrum of neuronal and network phenotypes in human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations

Author: Mok RSF, Zhang W, Sheikh TI, Pradeepan K, Fernandes IR, DeJong LC, Benigno G, Hildebrandt MR, Mufteev M, Rodrigues DC, Wei W, Piekna A, Liu J, Muotri AR, Vincent JB, Muller L, Martinez-Trujillo J, Salter MW, Ellis J

Product: Maestro Edge, Neural Module, CytoView MEA Plate,

Publication

STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells

Author: Blanch-Asensio A, Grandela C, Brandão KO, de Korte T, Mei H, Ariyurek Y, Yiangou L, Mol MPH, van Meer BJ, Kloet SL, Mummery CL, Davis RP

Product: Maestro Pro, Cardiac Module, Lumos, Lumos MEA Plate,

Publication

Use of a human induced pluripotent stem cell-derived dorsal root ganglion neurone model to study analgesics in vitro: proof of principle using lidocaine

Author: Smulders PSH, Hoope WT, Morcillo CB, Hermanides J, Hollmann MW, Weber NC

Product: Maestro Edge, Neural Module, CytoView MEA Plate,

Publication

Human-specific regulation of neural maturation identified by cross-primate transcriptomics

Author: Linker SB, Narvaiza I, Hsu JY, Wang M, Qiu F, Mendes APD, Oefner R, Kottilil K, Sharma A, Randolph-Moore L, Mejia E, Santos R, Marchetto MC, Gage FH

Product: Maestro Edge, Neural Module, CytoView MEA Plate,

Publication

Sequestration of gut pathobionts in intraluminal casts, a mechanism to avoid dysregulated T cell activation by pathobionts

Author: Sassone-Corsi M, Azriel S, Simon A, Ramanan D, Ortiz-Lopez A, Chen F, Yissachar N, Mathis D, Benoist C

Product: Maestro Edge, CytoView-Z Plate, Impedance Module,

Publication

Transcriptomic analysis in the striatum reveals the involvement of Nurr1 in the social behavior of prenatally valproic acid-exposed male mice

Author: Hyunju K, Ran-Sook W, Eun-Jeong Y, Han-Byeol K, Eun hwa J, Sangjoon L, Hehin I, Seonghan K, Hye-Sun K

Product: Maestro Pro, CytoView MEA Plate, Neural Module,

Publication

GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma

Author: T. Gargett, L. Ebert, N. Truong, P. Kollis, K. Sedivakova, W. Yu, E. Yeo, N. Wittwer, B. Gliddon, M. Tea, R. Ormsby, S. Poonnoose, J. Nowicki, O. Vittorio, D. Ziegler, S. Pitson and M. Brown

Product: Maestro Z, CytoView-Z Plate,

2022 Cell: Tissue- and cell-type-specific meolecular and functional sigantures

Publication

Tissue- and cell-type-specific molecular and functional signatures of 16p11.2 reciprocal genomic disorder across mouse brain and human neuronal models

Author: Tai D, Razaz P, Erdin S, Gao D, Wang J, Nuttle X, de Esch CE, Collins RL, Currall BB, O’Keefe K, Burt ND, Yadav R, Wang L, Mohajeri K, Aneichyk T, Ragavendran A, Stortchevoi A, Morini E, Ma W, Lucente D, Hastie A, Kelleher RJ, Perlis RH, Talkowski ME, Gusella JF

Product: Maestro Pro, Neural Module, CytoView MEA Plate,

Publication

Autophagic response of intestinal epithelial cells exposed to polystyrene nanoplastics

Author: X. Xu, Y. Feng, C. Han, Z. Yao, Y. Liu, C. Luo, and J. Sheng

Product: Exact FL,

Publication

Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity

Author: Hsieh Y-C, Negri J, He A, Pearse II RV, Liu L, Duong DM, Chibnik LB, Bennett DA, Seyfried NT, Young‑Pearse TL

Product: Maestro Edge, Neural Module, CytoView MEA Plate,

Publication

Characterization of N-terminal RYR2 variants outside CPVT1 hotspot regions using patient iPSCs reveal pathogenesis and therapeutic potential

Author: Stutzman M.J., Kim C.S., Tester D.J., Hamrick S.K., Dotzler S.M., Giudicessi J.R., Miotto M.C., Jeevan B. GC, Frank J, Marks A.R., Ackerman M.J.

Product: Maestro Pro, Cardiac Module, BioCircuit MEA Plate,

Publication

The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3

Author: S. Notova, F. Bonnardel , F. Rosato, L. Siukstaite, J. Schwaiger, J. H. Lim, N. Bovin, A. Varrot, Y. Ogawa, W. Römer, F. Lisacek and A. Imberty

Product: Exact FL,

Publication

MicroRNA-375 repression of Kruppel-like factor 5 improves angiogenesis in diabetic critical limb ischemia

Author: M. G. McCoy, A. Jamaiyar, G. Sausen, H. S. Cheng, D. Pérez-Cremades, R. Zhuang, J. Chen, P. P. Goodney, M. A. Creager, M. S. Sabatine, M. P. Bonaca and M. W. Feinberg

Product: Omni, Scratch Assay Module,

Publication

Hypermethylation of tumor suppressor lncRNA MEF2C-AS1 frequently happened in patients at all stages of colorectal carcinogenesis

Author: S. Qian, S. Lin, X. Xu, H. Bai, A. Yeerken, X. Ying, Z. Li, X. Fei, J. Yang, M. Tang, J. Wang, M. Jin and K. Chen

Product: Exact FL,

Publication

Neuronal avalanche dynamics and functional connectivity elucidate information propagation in vitro

Author: Heiney K, Ramstad OH, Fiskum V, Sandvig A, Sandvig I, Nichele S

Product: Maestro Pro, Neural Module, CytoView MEA Plate,

Publication

Small molecule-mediated allosteric activation of the base excision repair enzyme 8-oxoguanine DNA glycosylase and its impact on mitochondrial function

Author: G. Tian, S. R. Katchur, Y. Jiang, J. Briand, M. Schaber, C. Kreatsoulas, B. Schwartz, S. Thrall, A. M. Davis, S. Duvall, B. A. Kaufman and W. L. Rumsey

Product: Exact FL,