Resources
2020 mechanisms of QT prolongation on MEA system
Publication
Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block
Author: Tran PN, Sheng J, Randolph AL, Baron CA, Thiebaud N, Ren M, Wu M, Johannesen L, Volpe DA, Patel D, Blinova K, Strauss DG and Wu WW.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
2020 publication neuronal medium optimized for optogenetics
Publication
BrainPhys neuronal medium optimized for imaging and optogenetics in vitro
Author: Zabolocki M, McCormack K, van den Hurk M, Milky B, Shoubridge AP, Adams R, Jenne Tran J, Mahadevan-Jansen A, Reineck P, Thomas J, Hutchinson MR, Mak CKH, Añonuevo A, Chew LH, Hirst AJ, Lee VM, Knock E and Bardy C.
Product: Maestro Pro, Neural Module, Lumos MEA Plate, Lumos,
2020 publication on epilepsy and multielectrode array system
Publication
An epilepsy‐associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model
Author: Ahn LY, Coatti GC, Liu J, Gumus E, Schaffer AE, Miranda HC.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Immunotherapy presentation from festival of biologics
Video
Developing Immuno-therapies with Maestro Z
S. Chvatal, PhD
Product: Maestro Z, Impedance Module, CytoView-Z Plate, GxP Impedance Module, Impedance Automation Module,
2020 Publication on methadone and cortical organoids on MEA system
Publication
Methadone interrupts neural growth and function in human cortical organoids
Author: Yao H, Wu W, Cerf I, Zhao HW, Wang J, Negraes PD, Muotria AR, Haddad GG.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 publication on reduced gaba on neuronal excitability
Publication
Reduced GABAergic Neuron Excitability, Altered Synaptic Connectivity, and Seizures in a KCNT1 Gain-of-Function Mouse Model of Childhood Epilepsy
Author: Shore AN, Colombo S, Tobin WF, Petri S, Cullen ER, Dominguez S, Bostick CD, Beaumont MA, Williams D, Khodagholy D, Yang M, Lutz CM, Peng Y, Gelinas JN, Goldstein DB, Boland MJ, Frankel WN, Weston MC.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 EFSA publication on in vitro neurotoxicity
Publication
Establishment of an a priori protocol for the implementation and interpretation of an in‐vitro testing battery for the assessment of developmental neurotoxicity
Author: EFSA: European Food Safety Authority
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Toxicology hiPSC-derived neuronal co-culture for seizure on MEA
Publication
Applicability of hiPSC-derived neuronal co-cultures and rodent primary cortical cultures for in vitro seizure liability assessment
Author: Tukker AM, Wijnolts FMJ, de Groot A, Westerink RHS
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Neural Organoid Slice Protocol
Culture Protocol
Organotypic Slice Protocol from Stem Cell-derived Neuronal Organoids
Author: Axion BioSystems
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Journal of Industrial and Engineering Chemistry, 16 October 2020
Publication
Production of elastin-like recombinamer-based nanoparticles for docetaxel encapsulation and use as smart drug-delivery systems using a supercritical anti-solvent process
Author: R. Vallejo, J. Gonzalez-Valdivieso, M. Santos, S. Rodriguez-Rojo, and F.J. Arias
Product: Omni,
2020 publication toxicology MEA and neurotransmission
Publication
Synthetic cannabinoids enhanced ethanol-induced motor impairments through reduction of central glutamate neurotransmission
Author: Funada M, Takebayashi-Ohsawa M, Tomiyama K.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Patapia Neural Organoids (benos) video
Coffee Break Webinar
Neuronal Organoid activity mimics the fetal brain
Author: P. Zafeiriou, PhD
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Neucyte poster characterization of neural netowrk activity in neuron and glial co-cultures on MEA system
Poster
Functional Characterization of Neural Network Activity in Human iPSC-Derived Neuron/Glial Co-cultures
Author: Molla T, Lee C, Zhou P, Zhong W, Saavedra L, Davila J, Haag D
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Neucyte poster neurotoxic compounds on neural networks of cortical neurons on multwell MEA system
Poster
Comparison of Acute Effects of Neurotoxic Compounds on Network Activity in Human and Rodent Neural Cultures
Author: Saavedra L, Wallace K, Freudenrich T, Mall M, Mundy WR, Davila J, Südhof TC, Shafer TJ, Wernig M, Haag D
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Neucyte poster ipsc-derived neurons pathophysiology on MEA system
Poster
Application of Patient Generated iPSCs-Derived Neurons to Define the Pathophysiology of FXS Neurons
Author: Calado Botelho S, Saavedra L, Fua A, Huang T, Dávila J, Haag D, Dang V
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Neucyte poster neurotoxic compounds on neural networks on multwell MEA system
Poster
Comparison of Acute Effects of Neurotoxic Compounds in Neural Networks from Rodent and Human Neurons Using Microelectrode Arrays
Author: Freudenrich T, Wallace K, Haag D, Saavedra L, Mall M, Mundy WR, Davila J, Südhof TC, Wernig M, Shafer TJ
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Neucyte poster iPSC neural based model for seizure on microelectrode array system (MEA)
Poster
New iPSC-Based Neural In Vitro Approach for Seizure Liability Testing
Author: Saavedra L, Fua A, Dang V, Davila J, Haag D
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
SPS 2020 Poster Neucyte hiPSC-neurons on multiwell MEA system
Poster
Establishing an In Vitro Assay for Predicting Neurotoxicity Risks Using Functional Human iPSC-Derived Neurons
Author: Liu H, Zhong W, Saavedra L, Portmann T, Davila J, Haag D, Huang T.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Neucyte poster iPSC-neurons for drug discovery with multielectrode array system
Poster
Development of a Fully Defined, Synaptically Competent iPSC-Derived Neuronal Platform for Drug Discovery
Author: Saavedra L, Dang V, Fua A, Davila J, Haag D
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2020 Poster Neucyte in vitro neurotoxicity testing on MEA system
Poster
In Vitro Neurotoxicity Testing Using Functional Human iPSC-Derived Neurons
Author: Liu H, Saavedra L, Wallace K, Freudenrich T, Portmann T, Davila J, Shafer TJ, Wernig M, Haag D
Product: Maestro Pro, Neural Module, CytoView MEA Plate,