In vitro screening for seizure liability using microelectrode array technology

Bradley JA, Luithardt HH,  Metea MR, Strock CJ.

Toxicol Sci, 2018

Summary:

Discover how Maestro MEA technology makes it possible to identify seizurogenic drug effects at early stages of the development process, ensuring the development of safe candidate compounds.

Keywords: Seizure liability, neurotoxicity, safety, GABA antagonist, glycine receptor antagonist