Flaherty E, Zhu S, Barretto N, Cheng E, Deans PJM, Fernando MB, Schrode N, Francoeur N, Antoine A, Alganem K, Halpern M, Deikus D, Shah H, Fitzgerald M, Ladran I, Gochman P, Rapoport J, Tsankova NM, McCullumsmith R, Hoffman GE, Sebra R, Fang G, Brennand KJ.
Nature Genetics, 2019
Summary:
Learn how Axion's Maestro MEA was used to demonstrate how reduced neuronal activity in patient-derived NRXN1+/− hiPSC-neurons can be ameliorated by overexpression of individual control isoforms of the gene.
Keywords: patient derived neurons, human induced pluripotent stem cells
