Dissecting the functional consequences of de novo DNA methylation dynamics in human motor neuron differentiation and physiology

Ziller MJ, Ortega JA, Quinlan KA, Santos DP, Gu H, Martin EJ, Galonska C, Pop R, Maidl S, Di Pardo A, Huang M, Meltzer HY, Gnirke A, Heckman CJ, Meissner A, Kiskinis E.

Cell Stem Cell, 2018

Summary:

Discover how Maestro technology helped researchers use a human embryonic stem cell differentiation model to dissect the role of DNAme in directing somatic cell fate.