Co-stimulation with IL-1beta and TNF-alpha induces an inflammatory reactive astrocyte phenotype with neurosupportive characteristics in a human pluripotent stem cell model system

Hyvärinen T, Hagman S, Ristola M, Sukki L, Veijula K, Kreutzer J, Kallio P, Narkilahti S.

Sci Rep, 2019


Axion's Maestro MEA mutiwell technology enabled researchers to study neuron-astrocyte crosstalk and human brain disease in a dish.

Keywords: astrocyte, inflammation, interleukin-1beta, tumor necrosis factor-alpha, neurotoxicity, axonal growth, astrogliosis