Chao Li, Sue McCrone, Jay W. Warrick, David R. Andes, Zachary Hite, Cecilia F. Volk, Warren E. Rose and David J. Beebe
Lab on a Chip, 2nd March 2023
In this study, the authors aimed to develop a system to detect antimicrobial activity by using a an under-oil open microfluidic system (UOMS) to perform antimicrobial susceptibility testing (AST). The Axion BioSystems Omni was used to visualize the whole UOMS-AST device over time, and the Axion BioSystems Confluency algorithm easily calculated pathogen growth for all conditions. Altogether, the results suggest that the usage of UOMS-AST for detection of antimicrobial activity is promising, while it also has a high potential of commercialization.
