Design and optimization of optogenetic multiwell microelectrode array assays for evaluating functional neurotoxicity

Recreating physiological neural activity in vitro would be advantageous for screening neurotoxins. Optogenetics affords highly precise control of neural activity and, when coupled with multiwell microelectrode array (MEA) technology, enables new functional assays for neural models in vitro. Case studies will illustrate how optogenetic MEA assays can accelerate neurotoxicology studies.

Design and optomization of optogenetic multiwell microelectrode array assays for evaluating functional neurotoxicity Daniel Millard SOT2020