Maestro Pro System - Brochure

 

The premier bioelectronic assay system

Axion Maestro Pro multielectrode array system

 

IMAGINEMultielectrode array well bottom from multiwell plate

 

A simple assay...

Bioelectronic assays monitor in vitro cell health and behavior. Sensitive electrodes track cellular activity, while the culture remains undisturbed.

 

Flexible

Noninvasively measure activity anytime, as often as needed, while cells remain in an optimally controlled environment.

 

Easy

Use basic cell culture techniques to perform quantitative assays that deliver high-resolution, functional data – with no need for dyes, labels, or complicated steps.

 

Time-saving

Measure with the push of a button or schedule recordings ahead of time. No incubation steps or complex handling required with a mostly hands-free assay.

 

 

EXPLORENeural activity map from Axion software

Complex biology...

The versatility of the Maestro Pro makes it ideal for any lab. Monitor dynamic cellular activity and perform complex functional experiments with only basic cell culture.

 

Electrical Activity

Create detailed functional profiles of electrically active cells using microelectrode array (MEA) technology. Repeatedly measure from the same culture and track network development and activity.

  • Neurons
  • Cardiomyocytes
  • Skeletal muscles
  • Retinal cells
  • Primary or stem cells
  • 2D or 3D cultures

Cellular Kinetics

Monitor the health and behavior of any cell type using impedance-based technology. Bioelectrodes measure complex dynamic responses, capturing every minute to reveal detailed cellular kinetics.

  • Immuno-oncology
  • Cytotoxicity
  • Cell proliferation
  • Barrier function
  • Migration/invasion
  • Cell signaling

 

 

DISCOVERMaestro Pro multielectrode array system

The Maestro Pro

The latest technological advances to facilitate your research. The Maestro Pro features:

Dynamic responses

Detect key parameters of neural activity, network dynamics, and cardiac functionality, measure cell growth and cytolysis, barrier function, and signaling – all label-free and in real time.

Push-button acquisition

Simplify processes with Maestro’s automatically adjusted temperature and CO2 levels and integrated barcode scanner that conveniently tracks plate usage.

Precise cellular control

Recreate specific patterns of cellular activity using electrical stimulation or light pulses (with the Lumos™ optical stimulation system).

Integrated environment

Easily control temperature and CO2 levels while suppressing electrical noise and mechanical vibrations with Maestro’s smart environmental chamber. No need to take up incubator space.

High-throughput assay

Record from 6 up to 96 wells of MEA data, or 96 up to 384 wells of impedance data. The Maestro Pro is designed for the workload of busy labs.

On-the-go connectivity

Use the Impedance module to track changes in cell proliferation, viability, and cell death from any mobile device. No need to be in the lab.

 

 

Customize your MAESTRO PRO

Maestro Pro multiwell MEA system with software, plate and peripheral options

 

SOFTWARE MODULES

To expand your assay

The Maestro Pro platform is available with seven software modules. Select the software modules to match your assay needs:

Neural MEA software module

Neural - Measure electrical network behavior of neurons, including: activity, synchrony, and network oscillations, label-free.

cardiac MEA software module

Cardiac - Record the four key measures of functional cardiac performance: action potential, field potential, propagation, and contractility.

MEA viability software module

MEA Viability - Measure cell viability and coverage on MEA plates for a complete structure-function assay.

MEA Automation software module

MEA Automation - Automate Cardiac and Neural MEA assays with this API for interfacing with liquid handling platforms.

Impedance software module

Impedance - Track cell proliferation, viability, barrier function, immune cell-mediated killing, viral cytopathic effects, and more.

GxP Impedance software module

GxP Impedance - Achieve FDA 21 CFR Part 11 compliance in GMP/GLP labs with this version of the Impedance Software Module.

Z automation software module

Impedance Automation - Automate impedance assays with this API for interfacing with liquid handling platforms.

 

MULTIWELL PLATES

In a range of formats

All of Axion’s MEA and impedance assay multiwell plates can be used with the Maestro Pro system. Select the multiwell plates to match your assay needs:

Mutlielectrode array plate options for microplates and assays

 

BioCircuit MEA - Maestro MEA plates with an opaque well bottom delivering high-quality results at the lowest cost per well. Available in 96-, 48-, and 24-well formats.


CytoView MEA - The premium Maestro MEA plate with a transparent well bottom for cell visualization and assay multiplexing. Available in 96-, 48-, 24-, and 6-well formats.


Lumos MEA - Maestro MEA plates designed for use with the Lumos system, featuring a transparent well bottom and light-focusing lid. Available in 96-, 48-, 24-well plate formats.


CytoView-Z - The Maestro impedance plate with a transparent well bottom for cell visualization and assay multiplexing. Available in 384- and 96-well plate formats.