Resources

Publication

Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy

Author: A. Zink, D. Dai, A. Wittich, M. Henke, G. Pedrotti, S. Heiduschka, G. Santamaria, T. M. Pentimalli, C. Brueser, S. Notopoulou, A. R. Umar, A. Zhaivoron, L. Petersilie, C. Jerred, J. Bergmans, L. A. Neu, F. Schumacher, J. Keller-Findeisen, A. Rybak-Wolf, D. Stach, J. Reinshagen, U. Haferkamp, K. Krieg, A. Zaliani, L. Euro, A. Di Donfrancesco, C. Santanatoglia, E. Cappellozza, M. S. Cubero, M. Pavez-Giani, O. Bakumenko, D. Meierhofer, A. Foley, S. Morales-Gonzalez, I. Tolle, D. Herebian, D. Bonesso, G. Cecchetto, S. N. Wong, M. Moresco, A. Maresca, I. Decimo, F. De Sanctis, A. Adamo, M. J.W. Adjobo-Hermans, R. Duchi, M. Barandalla, M. Scaglia, A. Perota, C. Galli, B. Kleuser, L. Cyganek, C. Mühlhausen, L. Schlotawa, V. Tiranti, E. Mayatepek, I. Szabo, C. La Morgia, T. Klopstock, V. Carelli, F. Distelmaier, A. Rossi, N. Rajewsky, G. Ullah, S. Jakobs, C. R. Rose, S. Petrakis, F. Edenhofer, W. J.H. Koopman, P. Lisowski, A. Suomalainen, D. Brunetti, A. del Sol, E. Bottani, O. Pless, M. Schuelke, and A. Prigione

Product: Exact FL,

Publication

Human-specific features of the cerebellum and ZP2-regulated synapse development

Author: S. Kim, A. Cherskov, A. Sindhwani, S. Choi, H. Kim, M. Li, M. Zhang, X. Mato-Blanco, Y. Liu, N. Micali, D. M. Young, M. Estacion, Y. Zhang, J. M. Ruiz-Jiménez, A. Nadkarni, V. Luria, S. K. Sindhu, I. Chatterjee, A. Shibata, D. Liang, H. Cho, S. Park, A. Spajic, R. Kovner, M. Glavan, R. J. Chen, R. D. Risgaard, X. Li, S. Pochareddy, A. Karger, A. Huttner, Y. M. Morozov, E. W. Daadi, C. Colantuoni, K. T. Gobeske, J. J. Ely, P. R. Hof, M. M. Daadi, C. C. Sherwood, A. Duque, S. Ma, A. M.M. Sousa, S. G. Waxman, P. Rakic, G. Santpere, S. J. Sanders, and N. Sestan

Product: Maestro Pro, Neural Module, CytoView MEA Plate,

The 5-HT1A receptor antagonist WAY-100635 maleate promotes retinal ganglion cell differentiation and protects the retino-visual circuits

A reproducible and physiologically relevant human iPSC-derived platform for in vitro modeling of the neurocardiac junction

TNF alpha unmasks enteric malate aspartate shuttle dysfunction bridging Parkinson disease and intestinal inflammation

Extracellular Matrix Microspheres with Magnetically Labeled MSCs enable Functional Regeneration of the Osteo-Tendinous Junction

Autophagy dysfunction in iPSCs-derived neurons and midbrain organoids carrying a SNCA triplication

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

KCNQ1 D673N Variant Causes Loss of Adrenergic-Induced Cardiac Action Potential Shortening

PTBP1 knockdown reprograms glioma stem cells into neuronal-like cells and suppresses tumorigenesis via the DUSP5-ERK1/2 signaling pathway

Effects of acute fluctuations of extracellular Zinc on network activity of human iPSC-derived neurons; impact of NMDA Receptor and L-Type Calcium Channel Activation

Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell lines

lncRNA Glelr modulates microglia inflammatory programs in association with PU.1

In vitro and preclinical assessment of drug interactions between fluoroquinolones and a nonsteroidal anti-inflammatory drug predicting risk of seizure

IGFBP3 repression driven by inflammation links air pollution to placental and developmental defects

A Reproducible, Label-Free Platform for Real-Time Cytotoxicity and Hepatotoxicity Screening

Uncovering NMDA receptor-mediated high firing activity in excitatory human neurons

Early-stage quality—late-stage confidence: Neural induction quality control as a key to reproducible MEA-based neurotoxicity assays

Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy

Soluble α2δ-1, altered in disease CSF, modulates network homeostasis and rescues deficits in a neuropsychiatric mouse model

Radiation-induced neurotoxicity: investigating human neuronal damage in MEA-integrated microfluidic platforms

Human-specific features of the cerebellum and ZP2-regulated synapse development