Many neurological disorders are highly debilitating, and the current treatment options are limited to symptom reduction rather than providing a cure. Advances in differentiating iPSCs towards a variety of neural cell types have recently unveiled promising opportunities to understand neurological diseases using patient cells.
But the study of electrically active cells has been historically complex, hindering our advancements in human biology and treating diseases. Your models and experiments may look no different under the microscope but what about their electrical activity? How do you know your cells are communicating if you've never recorded from their network?