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The Axion MEA systems represent the next generation in multi-electrode array technology, providing unprecedented access to extracellular information at a reasonable cost.  | Compact set-up | | 64 and 768 channel systems | | Affordable single and multi-well MEAs | | 1, 6, 12, 24, 48, or 96 culture wells | | ANSI-compliant multi-well plates | | Customizable MEA configurations | | Low-noise Recordings | | Fully Integrated Stimulation circuitry | | Simultaneous Stimulation & Recording | | Complex impedance measurements | | Integrated heaters and controllers | | Flexible open-source software | 
Axion Biosystems' proprietary technology introduces two significant advances to the field of electrophysiology: (1) Novel microfabrication methods have been developed to produce low-cost, disposable multielectrode arrays, and (2) Proprietary integrated circuits (IC) have been developed to eliminate stimulation artifacts, enabling simultaneous stimulation and recording. The combination of these developments has been integrated into an easy-to-use system that allows for high throughput cell-based assays and superior electro-active tissue diagnostics. Axion offers these MEA systems in both single and multiwell formats.
The Muse: Axion’s 64 channel system
The Axion Muse platform introduces fully integrated stimulation and recording to MEA platforms while dramatically reducing the cost and complexity of MEA research. This efficient, flexible, and compact system is well suited for virtually any laboratory environment. | 64 stimulating and recording channels | | USB Interface for laptops or desktops | | Fast MEA insertion with auto MEA identification | | Ultra-thin, transparent, and inexpensive MEAs | | Fully integrated heater with software controls | | Compatible with upright & inverted microscopes | | Open-source software | 
The Maestro: Axion’s 768 channel system (under development )
Axion’s Maestro platform brings MEA technology to the high throughput arena, enabling analysis of neural networks and electroactive tissue at an unprecedented pace and scale. This system is well suited for large-scale cellular analysis in secondary drug screening applications.
| 768 stimulating and recording channels | | ANSI-Compliant Multiwell MEA plates | | Accommodates 6, 12, 24, 48, and 96 wells | | Fast MEA insertion with auto MEA-plate identification | | Ultra-thin, transparent, & affordable MEA plates | | Fully integrated heater with software controls | | Automated electrode characterization & diagnostics |
| Open-source software | 
Specifications
| Recording |
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Stimulation |
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Total Voltage Gain |
1200 (61dB) |
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Stimulation Modality |
Current with compliance voltage |
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Input referred Noise |
< 2µVRMS (200Hz-3KHz) |
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Stimulation Voltage (max.) |
±2V |
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Low Frequency corner |
0.5Hz — 500Hz (adj.), 40dB/dec |
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Stimulation Current (max.) |
±250µA |
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High Frequency corner |
1KHz — 20KHz (adj.), 20dB/dec |
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Simultaneous Stim. Values (max.) |
3 (Muse), 4 (Maestro) |
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Sample and Hold capability |
Simultaneous in all channels |
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Simultaneous Stimulation Channels |
64 (Muse), 768 (Maestro) |
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Sample Rate |
Up to 30KHz (128 channels) |
Artifact Recovery Time |
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| Temperature Control |
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Stimulating channels |
< 2ms |
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Range |
ambient (5°C min.) to 45°C |
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Recording channels |
< 400µs |
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Resolution |
±0.1°C |
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Electrode impedance measurement |
Maestro only |
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Last Updated ( Tuesday, 01 June 2010 09:18 )
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